Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL959050 | 0.82 | PTGIR (0.35) | MLYCD | |
| SCHEMBL22125280 | 0.80 | SMARCA2 (0.41) | HDAC4 | |
| SCHEMBL16528878 | 0.75 | TRPM8 (0.39) | TRPM8 | |
| SCHEMBL15553491 | 0.74 | TRPV4 (0.43) | MLYCDMRGPRX4P2RX7TRPV4HDAC4 | |
| SCHEMBL3443031 | 0.74 | PTK2 (0.49) | — | |
| SCHEMBL20357360 | 0.72 | MEN1 (0.44) | — | |
| SCHEMBL4279593 | 0.72 | HDAC4 (0.43) | MLYCDMRGPRX4P2RX7TRPV4HDAC4 | |
| SCHEMBL20357378 | 0.70 | POLQ (0.39) | — | |
| SCHEMBL22614097 | 0.69 | MRGPRX4 (0.39) | MLYCDMRGPRX4P2RX7TRPV4HDAC4 | |
| SCHEMBL3765907 | 0.68 | SMN1; SMN2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851473-B2 | Amide compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20080312226-A1 | Amide Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-18 | — | — | US | disclosed |
| EP-1813606-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312226-A1 | Amide Compound | FAAH, FAAH2, CNR2 | MLYCD 4474/4885MRGPRX4 344/4885P2RX7 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.