SCHEMBL3759818

SCHEMBL3759818

Oc1ccc(C23CC4(c5ccc(O)c(O)c5)CC(c5ccc(O)c(O)c5)(C2)CC(c2ccc(O)c(O)c2)(C3)C4)cc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.61
GAA P10253 2/20 0.61
MEN1 O00255 1/20 0.61
GFER P55789 1/20 0.61
KMT2A Q03164 1/20 0.61
APP P05067 2/20 0.42
TRPA1 O75762 2/20 0.39
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA4 P22748 2/20 0.37
CA6 P23280 2/20 0.37
LCK P06239 1/20 0.37
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
ALOX5 P09917 2/20 0.36
ALOX15 P16050 2/20 0.34
KDM4E B2RXH2 2/20 0.34
PTGS2 P35354 2/20 0.34
IGF1R P08069 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3756585 0.85 MEN1 (0.72) POLBGAAMEN1GFERKMT2A
SCHEMBL1972365 0.82 MEN1 (0.79) POLBGAAMEN1GFERKMT2A
SCHEMBL31159651 0.76 APP (0.56) POLBGAAMEN1GFERKMT2A
SCHEMBL559964 0.76 MEN1 (1.00) POLBGAAMEN1GFERKMT2A
SCHEMBL4606957 0.72 ESR1 (0.51) POLBGAAMEN1GFERKMT2A
SCHEMBL17532656 0.71 ESR1 (0.68) POLBGAAMEN1GFERKMT2A
SCHEMBL10080774 0.71 MEN1 (0.47) POLBGAAMEN1GFERKMT2A
SCHEMBL4582985 0.71 ALDH1A1 (0.37) POLBGAAMEN1GFERKMT2A
SCHEMBL4743330 0.70 ESR1 (0.69) POLBGAAMEN1GFERKMT2A
SCHEMBL20250898 0.69 KMT2A (0.44) POLBGAAMEN1GFERKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8084650-B2 Adamantane derivative, resin composition containing same, and optoelectronic member and sealing agent for electronic circuit using those IDEMITSU KOSAN CO., LTD. (JP) 2011-12-27 US disclosed
US-20100298491-A1 ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC MEMBER AND SEALING AGENT FOR ELECTRONIC CIRCUIT USING THOSE IDEMITSU KOSAN CO., LTD. (JP) 2010-11-25 US disclosed
EP-1985616-A1 ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC MEMBER AND SEALING AGENT FOR ELECTRONIC CIRCUIT USING THOSE Idemitsu Kosan Co., Ltd. (JP) 2008-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298491-A1 ADAMANTANE DERIVATIVE, RESIN COMPOSITION CONTAINING SAME, AND OPTOELECTRONIC MEMBER AND SEALING AGENT FOR ELECTRONIC CIRCUIT USING THOSE AOC1, ASIC1, ICAM1 POLB 2866/4885GAA 1740/4885MEN1 2523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.