Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630383 | 0.88 | LMNA (0.46) | LMNASLC22A6APEX1TSHRNFKB1 | |
| SCHEMBL18205582 | 0.80 | — | — | |
| SCHEMBL7261102 | 0.74 | — | — | |
| SCHEMBL8701311 | 0.73 | — | — | |
| SCHEMBL28246779 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL11625326 | 0.72 | SLC6A12 (0.41) | LMNATSHRITGB3ITGA2BSLC6A1 | |
| SCHEMBL2919235 | 0.72 | SLC6A1 (0.38) | LMNAALKBH5SUCNR1EGLN1TSHR | |
| Acetic Acid SCHEMBL11123447 | 0.70 | ALOX5 (0.49) | SLC22A6TSHRALOX5 | |
| SCHEMBL5077782 | 0.70 | NPSR1 (0.43) | LMNAALKBH5SUCNR1EGLN1SLC22A6 | |
| SCHEMBL6221344 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311700-A1 | Transdermal preparation for external use containing nonsterioidal antiinflammatory/analgesic agent | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2010-12-09 | — | — | US | disclosed |