Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3750240 | 0.89 | MDM2 (0.41) | MDM2ALDH1A1PKMHPGDHSD17B10 | |
| SCHEMBL3756840 | 0.79 | ALDH1A1 (0.46) | ALDH1A1PKMHPGDHSD17B10KMT2A | |
| SCHEMBL3761212 | 0.76 | LIPE (0.44) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL1979633 | 0.71 | MDM2 (0.58) | MDM2KMT2AMEN1TSHR | |
| SCHEMBL3683326 | 0.71 | ALDH1A1 (0.46) | MDM2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL4608857 | 0.71 | ALDH1A1 (0.44) | MDM2ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL3685438 | 0.69 | MEN1 (0.37) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL13170136 | 0.68 | LMNA (0.38) | ALDH1A1HPGDKMT2AMEN1TSHR | |
| SCHEMBL3681463 | 0.66 | KMT2A (0.40) | KMT2A | |
| SCHEMBL3686221 | 0.65 | TSHR (0.52) | MDM2KMT2AMEN1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8449898-B2 | Fungicidal mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-28 | — | — | US | disclosed |
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CORTEVA AGRISCIENCE LLC | 2010-09-23 | — | — | US | disclosed |
| EP-2187748-A2 | FUNGICIDAL COMPOUNDS AND MIXTURES | E. I. du Pont de Nemours and Company (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009055514-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CYP1B1, CYP1A1, NOX1 | MDM2 3870/4885ALDH1A1 440/4885PKM 2640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.