Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686221 | 0.88 | TSHR (0.52) | MDM2THRBTSHRTP53RAB9A | |
| SCHEMBL3682227 | 0.88 | MAPT (0.61) | MDM2THRBTSHRMEN1KMT2A | |
| SCHEMBL3682625 | 0.84 | RAB9A (0.56) | MDM2THRBTP53RAB9ANPC1 | |
| SCHEMBL1980541 | 0.79 | THRB (0.58) | MDM2THRBTP53RAB9ANPC1 | |
| SCHEMBL14372217 | 0.77 | RAB9A (0.64) | THRBTP53RAB9ANPC1MEN1 | |
| SCHEMBL3683326 | 0.75 | ALDH1A1 (0.46) | MDM2TSHRMEN1KMT2AMAPT | |
| SCHEMBL4492029 | 0.72 | TP53 (0.80) | THRBTP53RAB9ANPC1MEN1 | |
| SCHEMBL3759963 | 0.71 | MDM2 (0.42) | MDM2TSHRMEN1KMT2A | |
| SCHEMBL1575011 | 0.71 | TP53 (0.55) | THRBTP53RAB9ANPC1MEN1 | |
| SCHEMBL25263692 | 0.71 | CA12 (0.59) | THRBTP53RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CORTEVA AGRISCIENCE LLC | 2010-09-23 | — | — | US | claimed |
| EP-3122746-B1 | PHENYLPIPERIDINECARBOXAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2018-04-25 | — | — | EP | disclosed |
| EP-2187748-B1 | FUNGICIDAL COMPOUNDS AND MIXTURES | DU PONT (US) | 2017-07-05 | — | — | EP | disclosed |
| US-20170137417-A1 | PHENYLPIPERIDINECARBOXAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-18 | — | — | US | disclosed |
| US-20170137417-A1 | PHENYLPIPERIDINECARBOXAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-18 | — | — | US | disclosed |
| WO-2015144571-A1 | PHENYLPIPERIDINECARBOXAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2015-10-01 | — | — | WO | disclosed |
| US-8449898-B2 | Fungicidal mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-28 | — | — | US | disclosed |
| US-20130045948-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-02-21 | — | — | US | disclosed |
| EP-2509978-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E.I. Du Pont De Nemours And Company (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011072207-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-16 | — | — | WO | disclosed |
| US-20100286147-A1 | FUNGICIDAL AMIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2010-11-11 | — | — | US | disclosed |
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CORTEVA AGRISCIENCE LLC | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045948-A1 | AZOCYCLIC INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, NCEH1 | MDM2 3471/4885THRB 3436/4885TSHR 2095/4885 |
| US-20100286147-A1 | FUNGICIDAL AMIDES | NAT1, NOX1, CBR1 | MDM2 4261/4885THRB 4375/4885TSHR 3362/4885 |
| US-20100240619-A1 | FUNGICIDAL MIXTURES | CYP1B1, CYP1A1, NOX1 | MDM2 3870/4885THRB 4319/4885TSHR 2769/4885 |
| US-20170137417-A1 | PHENYLPIPERIDINECARBOXAMIDE DERIVATIVES AS FUNGICIDES | CYP1A1, PNPO, PADI1 | MDM2 1207/4885THRB 3602/4885TSHR 2973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.