Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631646 | 0.94 | NPSR1 (0.53) | NPSR1KMT2AMAPTSMN1; SMN2SLC6A3 | |
| SCHEMBL10923583 | 0.90 | NPSR1 (0.49) | NPSR1KMT2AMAPTSMN1; SMN2SLC6A3 | |
| SCHEMBL8778657 | 0.90 | THRA (0.56) | NPSR1KMT2AMAPTSMN1; SMN2SLC6A3 | |
| SCHEMBL434556 | 0.88 | KMT2A (0.59) | NPSR1KMT2AMAPTSMN1; SMN2SLC6A3 | |
| SCHEMBL29412194 | 0.88 | KMT2A (0.59) | NPSR1KMT2AMAPTSMN1; SMN2SLC6A3 | |
| SCHEMBL8405141 | 0.88 | NPSR1 (0.53) | NPSR1KMT2AMAPTSMN1; SMN2SLC6A3 | |
| SCHEMBL2484906 | 0.88 | KMT2A (0.49) | NPSR1KMT2AMAPTSMN1; SMN2SLC6A3 | |
| SCHEMBL28345751 | 0.88 | THRA (0.64) | NPSR1KMT2AMAPTSMN1; SMN2SLC6A3 | |
| SCHEMBL11579345 | 0.88 | THRA (0.64) | NPSR1KMT2AMAPTSMN1; SMN2SLC6A3 | |
| SCHEMBL8390875 | 0.88 | THRA (0.64) | NPSR1KMT2AMAPTSMN1; SMN2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107014914-A | A kind of method of formula isomers and nitrobenzoyl phenyl propane compounds while Analyze ＆ separate FCE-20124 is revived | 重庆医药高等专科学校 | 2017-08-04 | — | — | CN | claimed |
| US-7847998-B2 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL, INC. (US) | 2010-12-07 | — | — | US | claimed |
| CN-107014914-A | A kind of method of formula isomers and nitrobenzoyl phenyl propane compounds while Analyze ＆ separate FCE-20124 is revived | 重庆医药高等专科学校 | 2017-08-04 | — | — | CN | disclosed |
| EP-2969499-A1 | METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION | Transitions Optical, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| CN-102668157-B | Organic electroluminescence element, manufacturing method thereof, and organic electroluminescence display device | SHARP KK | 2014-11-26 | — | — | CN | disclosed |
| WO-2014158802-A1 | METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION | TRANSITIONS OPTICAL, INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140265010-A1 | METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION | TRANSITIONS OPTICAL LIMITED (IE) | 2014-09-18 | — | — | US | disclosed |
| US-20140264979-A1 | METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION | TRANSITIONS OPTICAL LIMITED (IE) | 2014-09-18 | — | — | US | disclosed |
| US-20140078583-A1 | Photochromic Article Having At Least Partially Crossed Polarized Photochromic-Dichroic And Fixed-Polarized Layers | TRANSITIONS OPTICAL, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-8582192-B2 | Polarizing photochromic articles | TRANSITIONS OPTICAL, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| CN-102668157-A | Organic electroluminescence element, manufacturing method thereof, and organic electroluminescence display device | SHARP KK | 2012-09-12 | — | — | CN | disclosed |
| US-20080123172-A1 | POLARIZING, PHOTOCHROMIC DEVICES AND METHODS OF MAKING THE SAME | TRANSITIONS OPTICAL LIMITED (IE) | 2008-05-29 | — | — | US | disclosed |
| US-20080096049-A1 | capable of switching between the two states in response to at least actinic radiation; thermally reversible | TRANSITIONS OPTICAL, INC. (US) | 2008-04-24 | — | — | US | disclosed |
| US-20080096048-A1 | Thermally reversible; absorption ratio greater than 2.3 | TRANSITIONS OPTICAL, INC. (US) | 2008-04-24 | — | — | US | disclosed |
| US-7349137-B2 | Polarizing, photochromic devices and methods of making the same | PPG INDUSTRIES OHIO, INC. (US) | 2008-03-25 | — | — | US | disclosed |
| US-20080051575-A1 | capable of switching between the two states in response to at least actinic radiation; thermally reversible | TRANSITIONS OPTICAL ,INC. (US) | 2008-02-28 | — | — | US | disclosed |
| US-20080045704-A1 | Thermally reversible; absorption ratio greater than 2.3; cell method | TRANSITIONS OPTICAL, INC. (US) | 2008-02-21 | — | — | US | disclosed |
| US-7256921-B2 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL, INC. (US) | 2007-08-14 | — | — | US | disclosed |
| US-20070053048-A1 | Polirizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2007-03-08 | — | — | US | disclosed |
| US-20050012998-A1 | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL LIMITED (IE) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045704-A1 | Thermally reversible; absorption ratio greater than 2.3; cell method | CCND3, CCND1, CCND2 | NPSR1 3046/4885KMT2A 1511/4885MAPT 4145/4885 |
| US-20080096048-A1 | Thermally reversible; absorption ratio greater than 2.3 | CCND1, CCND3, CCND2 | NPSR1 2873/4885KMT2A 1838/4885MAPT 4150/4885 |
| US-20080051575-A1 | capable of switching between the two states in response to at least actinic radiation; thermally reversible | CCND1, CCND2, CCNE1 | NPSR1 3617/4885KMT2A 1830/4885MAPT 4085/4885 |
| US-20080096049-A1 | capable of switching between the two states in response to at least actinic radiation; thermally reversible | CCND1, CCND2, CCNE1 | NPSR1 3617/4885KMT2A 1830/4885MAPT 4085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.