SCHEMBL4631646

SCHEMBL4631646

CCCc1ccccc1OC(=O)c1ccccc1.O=C(Oc1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.53
MAPT P10636 6/20 0.49
KMT2A Q03164 5/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
ALDH1A1 P00352 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
PKM P14618 1/20 0.48
SLC6A3 Q01959 1/20 0.48
PARP10 Q53GL7 1/20 0.46
LMNA P02545 2/20 0.46
SREBF2 Q12772 1/20 0.44
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
MEN1 O00255 1/20 0.43
JAK2 O60674 1/20 0.43
USP2 O75604 1/20 0.43
ESR1 P03372 1/20 0.43
GAA P10253 1/20 0.43
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3760693 0.94 NPSR1 (0.58) NPSR1MAPTKMT2ASMN1; SMN2TDP1
SCHEMBL10923583 0.85 NPSR1 (0.49) NPSR1MAPTKMT2ASMN1; SMN2TDP1
SCHEMBL8778657 0.85 THRA (0.56) NPSR1MAPTKMT2ASMN1; SMN2SLC6A3
SCHEMBL6119606 0.83 THRA (0.47) NPSR1THRATHRBHSD17B10PPARD
SCHEMBL29412194 0.82 KMT2A (0.59) NPSR1MAPTKMT2ASMN1; SMN2TDP1
SCHEMBL434556 0.82 KMT2A (0.59) NPSR1MAPTKMT2ASMN1; SMN2TDP1
SCHEMBL11579345 0.82 THRA (0.64) NPSR1MAPTKMT2ASMN1; SMN2SLC6A3
SCHEMBL8405141 0.82 NPSR1 (0.53) NPSR1MAPTKMT2ASMN1; SMN2ALDH1A1
SCHEMBL2484906 0.82 KMT2A (0.49) NPSR1MAPTKMT2ASMN1; SMN2ALDH1A1
SCHEMBL28345751 0.82 THRA (0.64) NPSR1MAPTKMT2ASMN1; SMN2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1613985-B1 OPTICAL FILMS COMPRISING ONE OR MORE POLYARYLATES OBTAINED FROM SPECIFIC PHENOLIC MOLECULES FERRANIA TECHNOLOGIES SPA (IT) 2008-05-14 EP disclosed
US-20060257512-A1 Optical films comprising one or more polyarylates obtained from specific phenolic molecules ANGIOLINI SIMONE 2006-11-16 US disclosed
US-7022772-B2 Optical film comprising polyarylates containing bis-(hydroxyphenyl)-fluorene-ortho-disubstituted bisphenols FERRARIA TECHNOLOGIES S.P.A. (IT) 2006-04-04 US disclosed
EP-1613985-A1 OPTICAL FILMS COMPRISING ONE OR MORE POLYARYLATES OBTAINED FROM SPECIFIC PHENOLIC MOLECULES Ferrania Technologies S.p.A. (IT) 2006-01-11 EP disclosed
EP-1205772-B1 Optical film comprising polyarylates containing bis-(hydroxyphenyl)-fluorene-ortho-disubstituted bisphenols FERRANIA SPA (IT) 2005-03-09 EP disclosed
WO-2004090585-A1 OPTICAL FILMS COMPRISING ONE OR MORE POLYARYLATES OBTAINED FROM SPECIFIC PHENOLIC MOLECULES FERRANIA TECHNOLOGIES S.P.A. (IT) 2004-10-21 WO disclosed
US-20040192848-A1 Optical film comprising polyarylates containing bis-(hydroxyphenyl)-fluorene-ortho-disubstituted bisphenols FERRANIA, S.P.A 2004-09-30 US disclosed
US-6632886-B2 Light stability, heat resistance, light transparency, high glass transition temperature (Tg) and good mechanical properties FERRANIA, S.P.A. (IT) 2003-10-14 US disclosed
US-20020091200-A1 Optical film comprising polyarylates containing bis-(hydroxyphenyl)-fluorene-ortho-disubstituted bisphenols FERRANIA S.P.A. 2002-07-11 US disclosed
EP-1205772-A2 Optical film comprising polyarylates containing bis-(hydroxyphenyl)-fluorene-ortho-disubstituted bisphenols FERRANIA S.p.A. (IT) 2002-05-15 EP disclosed