Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760693 | 0.88 | NPSR1 (0.58) | NPSR1LMNACYP3A4TSHRMAPT | |
| SCHEMBL8405147 | 0.83 | KMT2A (0.43) | NPSR1LMNACYP1A2CYP3A4MAOA | |
| SCHEMBL4631646 | 0.82 | NPSR1 (0.53) | NPSR1LMNAMAPTALDH1A1GAA | |
| SCHEMBL10923583 | 0.82 | NPSR1 (0.49) | NPSR1LMNATSHRMAPTGAA | |
| SCHEMBL8405084 | 0.81 | NPSR1 (0.49) | NPSR1MAPTALDH1A1KCNH2KMT2A | |
| SCHEMBL20457363 | 0.81 | LMNA (0.50) | NPSR1LMNACYP1A2CYP3A4MAOA | |
| SCHEMBL29617334 | 0.81 | KMT2A (0.55) | NPSR1LMNACYP1A2CYP3A4MAOA | |
| SCHEMBL9761656 | 0.80 | NPSR1 (0.48) | NPSR1CYP1A2CYP3A4TSHRCYP2C9 | |
| SCHEMBL29678040 | 0.80 | THRA (0.49) | NPSR1LMNACYP1A2CYP3A4TSHR | |
| SCHEMBL8778657 | 0.79 | THRA (0.56) | NPSR1LMNAMAPTGAATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567993-B1 | Thermosetting imide oligomer and manufacturing method of heat resistant laminated sheet using the same | KANEGAFUCHI CHEMICAL IND (JP) | 1999-07-14 | — | — | EP | disclosed |
| US-5397419-A | Dissolving in solvent, coating or impregnation to form prepreg, heating, pressurization; heat resistant paints, electronics | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0567993-A1 | Thermosetting imide oligomer and manufacturing method of heat resistant laminated sheet using the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-11-03 | — | — | EP | disclosed |