SCHEMBL3761929

SCHEMBL3761929

CCc1ccc(OCCOC(=O)C(=O)OCCOc2ccc(CC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.53
MAPT P10636 3/20 0.53
ALDH1A1 P00352 2/20 0.53
HPGD P15428 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.51
RXRA P19793 1/20 0.51
RXRB P28702 1/20 0.51
KDM4E B2RXH2 1/20 0.50
KMT2A Q03164 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
HTT P42858 1/20 0.47
MEN1 O00255 1/20 0.47
HSP90AA1 P07900 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5929490 0.84 MAPT (0.62) LMNAMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL28794338 0.82 THRB (0.67) LMNAMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL3774318 0.81 LMNA (0.59) LMNAMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL15855594 0.80 TDP1 (0.55) LMNAMAPTSMN1; SMN2L3MBTL1RXRA
SCHEMBL18477954 0.80 L3MBTL1 (0.70) LMNAMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL24844505 0.78 THRB (0.61) LMNAMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL14579984 0.78 ALDH1A1 (0.56) LMNAMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL21430444 0.78 LMNA (0.53) LMNAMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL8277617 0.78 L3MBTL1 (0.68) LMNAMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL17445912 0.78 ALDH1A1 (0.66) LMNAMAPTALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8978553-B2 Heat-sensitive lithographic printing plates MITSUBISHI PAPER MILLS LIMITED (JP) 2015-03-17 US disclosed
US-20120192740-A1 FOUNTAIN SOLUTION COMPOSITION FOR LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING METHOD MITSUBISHI PAPER MILLS LIMITED (JP) 2012-08-02 US disclosed
US-20100307359-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATES MITSUBISHI PAPER MILLS LIMITED (JP) 2010-12-09 US disclosed