Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9336496 | 0.74 | KDM4E (0.32) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL377052 | 0.74 | KDM4E (0.36) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL15767506 | 0.73 | KMT2A (0.35) | HPGDALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL10359139 | 0.73 | KDM4E (0.33) | ALDH1A1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL22889987 | 0.72 | RXFP1 (0.40) | RXFP1HPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL15767643 | 0.71 | AAK1 (0.42) | RXFP1ALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL13117392 | 0.71 | HTT (0.40) | RXFP1HPGDALDH1A1CNR1CNR2 | |
| SCHEMBL9952846 | 0.70 | HSD17B10 (0.49) | RXFP1HPGDALDH1A1NPC1MAPK1 | |
| SCHEMBL16599646 | 0.69 | RAB9A (0.40) | RXFP1ALDH1A1RAB9ANPC1MAPK1 | |
| SCHEMBL18809145 | 0.69 | ALDH1A1 (0.35) | ALDH1A1MAPK1HSD17B10MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305330-A1 | Process for preparing 2-alkyl-3-halo-6-nitrilpyridine and its carboxylic acid and ester derivatives | Synergetica Changzhou Chemical Company (CN) | 2010-12-02 | — | — | US | disclosed |