SCHEMBL3763286

SCHEMBL3763286

CCc1cc(Nc2cc(C)c(CCc3ccccc3)c3c2C(=O)OC32c3ccccc3Oc3ccccc32)ccc1C

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
BRCA1 P38398 1/20 0.32
HSD17B10 Q99714 1/20 0.32
P2RY4 P51582 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671207 0.85 ALDH1A1 (0.42) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL395637 0.85 ALDH1A1 (0.35) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL9801536 0.83 ALDH1A1 (0.35) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL11003355 0.73 HPGD (0.39) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL387762 0.73 PRKCB (0.36) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL9848550 0.72 POLB (0.36) ALDH1A1HPGDHSD17B10
SCHEMBL11688939 0.72 EGFR (0.35) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL387083 0.71 NPSR1 (0.38) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL3974160 0.70 ALDH1A1 (0.39) ALDH1A1CYP2C9HPGDALOX15ALOX12
SCHEMBL9565549 0.70 HPGD (0.38) ALDH1A1CYP2C9HPGDALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8978553-B2 Heat-sensitive lithographic printing plates MITSUBISHI PAPER MILLS LIMITED (JP) 2015-03-17 US disclosed
US-20120192740-A1 FOUNTAIN SOLUTION COMPOSITION FOR LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING METHOD MITSUBISHI PAPER MILLS LIMITED (JP) 2012-08-02 US disclosed
US-20100307359-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATES MITSUBISHI PAPER MILLS LIMITED (JP) 2010-12-09 US disclosed
US-5407892-A Using ampholytic latex as binder; support coated with composition containing stilt agent, binder and anionic microcapsules MITSUBISHI PAPER MILLS LIMITED (JP) 1995-04-18 US disclosed
US-5288687-A Having dried coating of amphoteric latex binder with anionic microcapsules containing color former MITSUBISHI PAPER MILLS LIMITED (JP) 1994-02-22 US disclosed
US-5091357-A Intermediate layer containing inorganic powder, aqueous adhesive, carboxymethyl cellulose; prevention of scum adhesion to a thermal head MITSUBISHI PAPER MILLS LIMITED (JP) 1992-02-25 US disclosed
US-5064806-A CONTAINING AN ALKYLAMMONIUM SALT; HIGH COLOR DENSITY, LOW BACKGROUND STRAIN MITSUBISHI PAPER MILLS LIMITED (JP) 1991-11-12 US disclosed
US-4996183-A Minimization of head stain MITSUBISHI PAPER MILLS, LIMITED (JP) 1991-02-26 US disclosed
US-4889841-A 2-BENZYLOXYNAPHTHALENE AND P-BENZYLBIPHENYL ADDITIVES; NONFOGGING; THERMAL RESPONSE, NONADHERING MITSUBISHI PAPER MILLS LIMITED (JP) 1989-12-26 US disclosed
US-4576831-A Process for producing heat-sensitive recording paper FUJI PHOTO FILM CO., LTD. (JP) 1986-03-18 US disclosed