Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20508884 | 1.00 | MEN1 (0.45) | MEN1HPGDKMT2AHSD17B10BRD4 | |
| SCHEMBL16136368 | 0.78 | FPR2 (0.48) | BRD4OPRD1OPRK1CYP1A2CYP3A4 | |
| Efetozole SCHEMBL2109012 | 0.77 | BRD4 (0.51) | MEN1HPGDKMT2AHSD17B10BRD4 | |
| Efetozole SCHEMBL21698044 | 0.77 | BRD4 (0.51) | MEN1HPGDKMT2AHSD17B10BRD4 | |
| SCHEMBL4077931 | 0.76 | MAPT (0.35) | ALDH1A1 | |
| SCHEMBL18516672 | 0.76 | POLB (0.40) | MEN1KMT2AHSD17B10OPRD1OPRK1 | |
| SCHEMBL11431373 | 0.76 | BRD4 (0.38) | MEN1HPGDKMT2AHSD17B10BRD4 | |
| SCHEMBL28292973 | 0.76 | OPRD1 (0.43) | MEN1HPGDKMT2AHSD17B10BRD4 | |
| SCHEMBL28780266 | 0.76 | ALDH1A1 (0.47) | MEN1HPGDKMT2AHSD17B10BRD4 | |
| Efetozole SCHEMBL10996922 | 0.76 | BRD4 (0.50) | MEN1HPGDKMT2AHSD17B10BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451779-A2 | ETOMIDATE ANALOGUES THAT DO NOT INHIBIT ADRENOCORTICAL STEROID SYNTHESIS | The General Hospital Corporation (US) | 2012-05-16 | — | — | EP | disclosed |