Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3757509 | 0.82 | MEN1 (0.54) | HRH3MEN1KMT2ACCR3GAA | |
| SCHEMBL3763647 | 0.80 | HDAC3 (0.50) | MEN1KMT2ACCR3 | |
| SCHEMBL3762996 | 0.78 | ACHE (0.49) | MEN1KMT2AKDM4EHTTALDH1A1 | |
| SCHEMBL4658026 | 0.78 | CCR3 (0.63) | HRH3CCR3GAAKDM4EHTT | |
| SCHEMBL4657913 | 0.73 | CCR3 (0.56) | CCR3GAAKDM4EHTTALDH1A1 | |
| SCHEMBL5188520 | 0.73 | CCR3 (0.48) | MEN1KMT2ACCR3KDM4EMAPT | |
| SCHEMBL4658054 | 0.71 | CCR3 (0.60) | CCR3GAAHTTALDH1A1 | |
| SCHEMBL3761870 | 0.69 | KDM4E (0.47) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL5163035 | 0.69 | CCR3 (0.50) | CCR3GAAKDM4EHTTALDH1A1 | |
| SCHEMBL3757507 | 0.69 | CCR3 (0.47) | HRH3MEN1KMT2ACCR3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842812-B2 | Substituted 5-aminomethy1-1H-pyrrole-2-carboxylic acid amides | GRUENENTHAL GMBH (DE) | 2010-11-30 | — | — | US | disclosed |
| US-20070135494-A1 | Substituted 5-aminomethyl-1H-pyrrole-2-carboxylic acid amides | GRUENENTHAL GMBH (DE) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135494-A1 | Substituted 5-aminomethyl-1H-pyrrole-2-carboxylic acid amides | AVPR2, GPR119, AVPR1B | HRH3 336/4885MEN1 2122/4885KMT2A 1381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.