SCHEMBL376419

SCHEMBL376419

CNc1ccc(C(c2ccc(NC)c(N)c2)(C(F)(F)F)C(F)(F)F)cc1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
HSD17B10 Q99714 2/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 2/20 0.44
MAPT P10636 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
GFER P55789 1/20 0.44
PRKCI P41743 1/20 0.43
KIF11 P52732 3/20 0.38
ESR1 P03372 2/20 0.36
ESR2 Q92731 1/20 0.36
CFTR P13569 1/20 0.36
EGFR P00533 1/20 0.33
PKM P14618 2/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29539971 1.00 MEN1 (0.45) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL26417533 0.88 MEN1 (0.37) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL14934058 0.85 MEN1 (0.45) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL115650 0.85 ALDH1A1 (0.59) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL28401754 0.82 MEN1 (0.42) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL25533949 0.81 GAA (0.63) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL26417681 0.81 PRKCI (0.56) MAPK1GAAMAPTPRKCIRAB9A
SCHEMBL376030 0.81 MAPT (0.47) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL29540627 0.81 MAPT (0.47) MEN1KMT2AHSD17B10ALOX15TSHR
SCHEMBL28991341 0.81 MEN1 (0.41) MEN1KMT2AHSD17B10ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583957-B2 Fluoropolymer-containing composition and molded article DAIKIN INDUSTRIES, LTD. (JP) 2026-03-24 US disclosed
EP-4253432-B1 FLUOROPOLYMER, AQUEOUS LIQUID DISPERSION, COMPOSITION, AND CROSSLINKED PRODUCT DAIKIN IND LTD (JP) 2026-02-25 EP disclosed
US-20250340727-A1 POLYMER BLEND, CROSSLINKABLE COMPOSITION AND ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2025-11-06 US disclosed
US-12448466-B2 Method for producing perfluoroelastomer and composition DAIKIN INDUSTRIES, LTD. (JP) 2025-10-21 US disclosed
EP-4632002-A1 POLYMER BLEND, CROSSLINKABLE COMPOSITION, AND ARTICLE Daikin Industries, Ltd. (JP) 2025-10-15 EP disclosed
EP-4619468-A2 FLUID PLASTICIZERS INCLUDING FLUORINATED ORGANIC COMPOUNDS FOR USE IN CURABLE FLUOROPOLYMER COMPOSITIONS AND FLUOROELASTOMER COMPOSITIONS, AND METHODS FOR IMPROVING PROCESSABILITY AND LOW TEMPERATURE USE PROPERTIES OF SUCH COMPOSITIONS Greene, Tweed Technologies, Inc. (US) 2025-09-24 EP disclosed
US-20250171564-A1 METHOD FOR PRODUCING PERFLUOROELASTOMER AND COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2025-05-29 US disclosed
US-20250171614-A1 CROSSLINKABLE ELASTOMER COMPOSITION AND FLUORORUBBER MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2025-05-29 US disclosed
US-12304984-B2 Composition containing fluorine-containing polymer and crosslinked article DAIKIN INDUSTRIES, LTD. (JP) 2025-05-20 US disclosed
US-12297341-B2 Fluorine-containing elastomer composition and article DAIKIN INDUSTRIES, LTD. (JP) 2025-05-13 US disclosed
US-20070098978-A1 Surface-coated sealing material DAIKIN INDUSTRIES, LTD. (JP) 2007-05-03 US disclosed
EP-1741748-A1 FLUORINE-CONTAINING ELASTOMER COMPOSITION AND MOLDED ARTICLE FORMED THEREFROM Daikin Industries, Ltd. (JP) 2007-01-10 EP disclosed
US-20060293432-A1 Fluorine-containing elastomer composition and molded article comprising the same DAIKIN INDUSTRIES, LTD. 2006-12-28 US disclosed
EP-1688648-A1 SURFACE-COATED SEALING MATERIAL Daikin Industries, Ltd. (JP) 2006-08-09 EP disclosed
US-6878778-B1 Fluoroelastomer composition for crosslinking DAIKIN INDUSTRIES, LTD. (JP) 2005-04-12 US disclosed
US-20050070637-A1 Crosslinkable elastomer composition and formed product comprising the same DAIKIN INDUSTRIES, LTD. (JP) 2005-03-31 US disclosed
US-20050020748-A1 Molded article of a crosslinked fluorine-containing elastomer containing an inorganic filler; heat resistance for use at high temperature, resistance to high density plasma; use sealing semiconductor manufacturing equipment DAIKIN INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1464671-A1 ELASTOMER FORMED PRODUCT Daikin Industries, Ltd. (JP) 2004-10-06 EP disclosed
EP-1464676-A1 CROSSLINKABLE ELASTOMER COMPOSITION AND FORMED PRODUCT COMPRISING THE SAME Daikin Industries, Ltd. (JP) 2004-10-06 EP disclosed
EP-1245635-A1 FLUOROELASTOMER COMPOSITION FOR CROSSLINKING Daikin Industries, Ltd. (JP) 2002-10-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583957-B2 Fluoropolymer-containing composition and molded article AOC2, AOC1, AOC3 MEN1 66/4885KMT2A 478/4885HSD17B10 2894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.