Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 1/20 | 0.55 |
| ▸ | RHOA | P61586 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3771503 | 1.00 | RHOC (0.55) | RHOCRHOAKCNK3P2RX1LMNA | |
| SCHEMBL6813377 | 0.87 | NPSR1 (0.64) | LMNAMEN1HTTKMT2AHDAC3 | |
| SCHEMBL6813375 | 0.87 | NPSR1 (0.64) | LMNAMEN1HTTKMT2AHDAC3 | |
| SCHEMBL3771065 | 0.85 | KCNK3 (0.58) | KCNK3HDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL3772371 | 0.85 | KCNK3 (0.58) | KCNK3HDAC3CYP2C9HDAC1HDAC6 | |
| SCHEMBL4089254 | 0.84 | ACKR3 (0.44) | RHOCRHOAKCNK3LMNAMAPT | |
| SCHEMBL3771456 | 0.81 | MEN1 (0.55) | KCNK3MEN1RAB9AKMT2AKCNK9 | |
| SCHEMBL3779790 | 0.81 | MEN1 (0.55) | KCNK3MEN1RAB9AKMT2AKCNK9 | |
| SCHEMBL3768839 | 0.81 | MEN1 (0.60) | MEN1RAB9AKMT2AMAPT | |
| SCHEMBL3772902 | 0.81 | MEN1 (0.60) | MEN1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | claimed |
| WO-2009103778-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2009-08-27 | — | — | WO | claimed |
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | IL1B, LITAF, CYP11B1 | RHOC 4277/4885RHOA 4089/4885KCNK3 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.