Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.58 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.58 |
| ▸ | F2R | P25116 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772371 | 1.00 | KCNK3 (0.58) | KCNK3KCNK9F2RPTGS1PTGES | |
| SCHEMBL3779790 | 0.87 | MEN1 (0.55) | KCNK3KCNK9F2RPTGES | |
| SCHEMBL3771456 | 0.87 | MEN1 (0.55) | KCNK3KCNK9F2RPTGES | |
| SCHEMBL3766322 | 0.85 | KCNK3 (0.56) | KCNK3KCNK9 | |
| SCHEMBL3776657 | 0.85 | KCNK3 (0.56) | KCNK3KCNK9 | |
| SCHEMBL3764435 | 0.85 | RHOC (0.55) | KCNK3KCNK9PTGS1HDAC3CYP2C9 | |
| SCHEMBL3771503 | 0.85 | RHOC (0.55) | KCNK3KCNK9PTGS1HDAC3CYP2C9 | |
| SCHEMBL3777602 | 0.85 | F2R (0.55) | KCNK3KCNK9F2RPTGES | |
| SCHEMBL3777535 | 0.85 | PTGES (0.52) | KCNK3KCNK9PTGES | |
| SCHEMBL3770507 | 0.85 | PTGES (0.66) | KCNK3KCNK9F2RPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | claimed |
| WO-2009103778-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2009-08-27 | — | — | WO | claimed |
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | IL1B, LITAF, CYP11B1 | KCNK3 1692/4885KCNK9 1283/4885F2R 875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.