Butane

Butane

SCHEMBL3765407

CCCC.COc1ccc(CO[PH](=O)O)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.47
AGXT P21549 2/20 0.47
APP P05067 3/20 0.46
HTT P42858 1/20 0.46
NPC1 O15118 1/20 0.45
POLB P06746 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
CALM1 P0DP23 1/20 0.43
FFAR1 O14842 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
LDHA P00338 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8507266 0.95 IDO1 (0.52) IDO1AGXTAPPHTTNPC1
Butane SCHEMBL8002745 0.84 IDO1 (0.42) IDO1APPTDP1TAAR1ALDH1A1
Butane SCHEMBL16290769 0.83 PTGS2 (0.42) POLBCALM1ALDH1A1
Butane SCHEMBL9443644 0.82 APP (0.41) APPNPC1RAB9ASMN1; SMN2TDP1
Butane SCHEMBL3196642 0.82 AGXT (0.44) IDO1AGXTNPC1RAB9ATAAR1
Butane SCHEMBL5292210 0.81 IDO1 (0.53) IDO1AGXTTAAR1
Butane SCHEMBL8010999 0.81 PTGS1 (0.53) HTTRAB9ASMN1; SMN2FFAR1ALDH1A1
Butane SCHEMBL6056712 0.81 IDO1 (0.42) IDO1AGXTAPPPOLBTDP1
Butane SCHEMBL2802241 0.81 POLB (0.42) IDO1APPPOLBFFAR1ALDH1A1
Butane SCHEMBL1238313 0.80 ALDH1A1 (0.46) IDO1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230180761-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2023-06-15 US disclosed
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2023-04-25 US disclosed
US-20200196607-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2020-06-25 US disclosed
EP-3578541-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITION, AND PROCESSES, RELATED THERETO Dow AgroSciences LLC (US) 2019-12-11 EP disclosed
EP-3578543-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Dow AgroSciences LLC (US) 2019-12-11 EP disclosed
EP-3578542-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Dow AgroSciences LLC (US) 2019-12-11 EP disclosed
EP-3526192-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Dow AgroSciences LLC (US) 2019-08-21 EP disclosed
EP-3283458-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed
EP-3283460-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITION, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed
EP-3283459-B1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2019-05-22 EP disclosed
WO-2016168058-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-10-20 WO disclosed
WO-2016168059-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-10-20 WO disclosed
US-7897313-B2 Electrostatic latent image bearing member, and image forming apparatus and process cartridge using the electrostatic latent image bearing member RICOH COMPANY LIMITED (JP) 2011-03-01 US disclosed
US-7851114-B2 Electrostatic latent image bearing member, and image forming apparatus, process cartridge, and image forming method using the same RICOH COMPANY LIMITED (JP) 2010-12-14 US disclosed
US-20070254224-A1 ELECTROSTATIC LATENT IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE ELECTROSTATIC LATENT IMAGE BEARING MEMBER RICOH COMPANY LIMITED (JP) 2007-11-01 US disclosed
EP-1850184-A1 Electrostatic latent image bearing member, and image forming apparatus and process cartridge using the electrostatic latent image bearing member Ricoh Company, Ltd. (JP) 2007-10-31 EP disclosed
US-20070117033-A1 ELECTROSTATIC LATENT IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE FORMING METHOD USING THE SAME RICOH COMPANY LIMITED (JP) 2007-05-24 US disclosed
US-6172176-B1 Electrophotographic photoconductor and aromatic polycarbonate resin for use therein RICOH COMPANY, LTD. (JP) 2001-01-09 US disclosed
US-5976746-A ELECTROCONDUCTIVE SUPPORT; PHOTOCONDUCTIVE LAYER RICOH COMPANY, LTD. (JP) 1999-11-02 US disclosed
EP-0447189-A1 5-Hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors MERCK FROSST CANADA INC. (CA) 1991-09-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11632957-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD IDO1 143/4885AGXT 632/4885APP 3329/4885
US-20230180761-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD IDO1 143/4885AGXT 632/4885APP 3329/4885
US-20200196607-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD IDO1 143/4885AGXT 632/4885APP 3329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.