Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 4/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | DTYMK | P23919 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708975 | 0.85 | KDM4E (0.36) | ACKR3HRH2HRH1SIGMAR1 | |
| SCHEMBL8618331 | 0.83 | GPR119 (0.49) | GPR119 | |
| SCHEMBL5228089 | 0.81 | SMN1; SMN2 (0.53) | ACKR3CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL26826092 | 0.78 | ALDH1A1 (0.62) | ACKR3CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9744195 | 0.78 | SMN1; SMN2 (0.55) | ACKR3CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14768643 | 0.75 | SMN1; SMN2 (0.53) | ACKR3SMN1; SMN2GPR119 | |
| SCHEMBL2023366 | 0.75 | SMN1; SMN2 (0.72) | CHRM2CHRM4CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL20873847 | 0.75 | USP2 (0.53) | ACKR3CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL4772966 | 0.74 | GPR119 (0.52) | GPR119 | |
| SCHEMBL3905754 | 0.74 | GBA1 (0.49) | ACKR3CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | TOP2A, TOP1, TOP2B | ACKR3 4838/4885CHRM2 4610/4885CHRM4 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.