Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.67 |
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.61 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.61 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KIT | P10721 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764438 | 0.87 | HTR2B (0.58) | RAB9ANPC1KCNK3KCNK9SMN1; SMN2 | |
| SCHEMBL3771105 | 0.86 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL3766917 | 0.86 | F2R (0.63) | RAB9ANPC1ALDH1A1PKMALOX15 | |
| SCHEMBL3775418 | 0.86 | ACKR3 (0.61) | RAB9ANPC1KCNK3KCNK9ACKR3 | |
| SCHEMBL3764424 | 0.86 | HTR2B (0.63) | RAB9ANPC1ACKR3SMN1; SMN2PKM | |
| SCHEMBL3766555 | 0.86 | HTR2B (0.57) | RAB9ANPC1SMN1; SMN2PKMALOX15 | |
| SCHEMBL3771747 | 0.85 | KCNK3 (0.63) | RAB9ANPC1KCNK3KCNK9ACKR3 | |
| SCHEMBL3766651 | 0.83 | PKM (0.55) | RAB9ANPC1KCNK3KCNK9ACKR3 | |
| SCHEMBL3771553 | 0.83 | KCNK3 (0.63) | KCNK3KCNK9HTR2B | |
| SCHEMBL8198182 | 0.82 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | claimed |
| WO-2009103778-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2009-08-27 | — | — | WO | claimed |
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | disclosed |
| WO-2009103778-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2009-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | IL1B, LITAF, CYP11B1 | RAB9A 2083/4885NPC1 145/4885KCNK3 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.