Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | ATP4A | P20648 | 2/20 | 0.44 |
| ▸ | ATP4B | P51164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11466220 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTHSD17B10HPGDGLA | |
| SCHEMBL13002963 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTHSD17B10ARHPGD | |
| SCHEMBL2174125 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTHSD17B10ARHPGD | |
| SCHEMBL9891492 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTHSD17B10ARHPGD | |
| Hydrochloric Acid SCHEMBL6371660 | 0.77 | ALDH1A1 (0.93) | ALDH1A1MAPTHSD17B10ARHPGD | |
| SCHEMBL15728787 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTHSD17B10ARHPGD | |
| SCHEMBL2483879 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MAPTHSD17B10ARHPGD | |
| SCHEMBL15728783 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MAPTHSD17B10ARHPGD | |
| SCHEMBL3763258 | 0.75 | MAOA (0.50) | ALDH1A1MAPTHSD17B10AR | |
| SCHEMBL3147980 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDGLAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851473-B2 | Amide compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20080312226-A1 | Amide Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-18 | — | — | US | disclosed |
| CN-101103007-A | Amide compound | TAKEDA PHARMACEUTICAL (JP) | 2008-01-09 | — | — | CN | disclosed |
| EP-1813606-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312226-A1 | Amide Compound | FAAH, FAAH2, CNR2 | ALDH1A1 353/4885MAPT 3805/4885HSD17B10 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.