⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14257118 | 1.00 | — | — | |
| SCHEMBL3767656 | 1.00 | — | — | |
| SCHEMBL5880313 | 0.83 | TSHR (0.32) | — | |
| SCHEMBL3767458 | 0.83 | TSHR (0.32) | — | |
| SCHEMBL3767455 | 0.83 | TSHR (0.32) | — | |
| SCHEMBL12374920 | 0.82 | — | — | |
| SCHEMBL4812019 | 0.81 | GSK3B (0.32) | — | |
| SCHEMBL9649935 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL4812013 | 0.81 | GSK3B (0.32) | — | |
| SCHEMBL9649932 | 0.81 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7847093-B2 | Processes for the preparations of cefepime | SANDOZ AG (CH) | 2010-12-07 | — | — | US | claimed |
| EP-2218723-A2 | Processes for the preparations of cefepime | Sandoz AG (CH) | 2010-08-18 | — | — | EP | claimed |
| US-20070105830-A1 | Processes for the preparations of cefepime | SANDOZ AG (CH) | 2007-05-10 | — | — | US | claimed |
| EP-1618114-A2 | PROCESSES FOR THE PREPARATIONS OF CEFEPIME | Sandoz AG (CH) | 2006-01-25 | — | — | EP | claimed |
| WO-2004092183-A2 | PROCESSES FOR THE PREPARATIONS OF CEFEPIME | SANDOZ AG (CH) | 2004-10-28 | — | — | WO | claimed |
| US-7847093-B2 | Processes for the preparations of cefepime | SANDOZ AG (CH) | 2010-12-07 | — | — | US | disclosed |
| EP-2218723-A2 | Processes for the preparations of cefepime | Sandoz AG (CH) | 2010-08-18 | — | — | EP | disclosed |
| WO-2008047376-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEPHALOSPORIN ANTIBIOTIC | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2008-04-24 | — | — | WO | disclosed |
| US-7345169-B2 | Process for the preparation of cephalosporin antibiotic | ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) | 2008-03-18 | — | — | US | disclosed |
| US-20070105830-A1 | Processes for the preparations of cefepime | SANDOZ AG (CH) | 2007-05-10 | — | — | US | disclosed |
| US-7098329-B2 | Process for the preparation of a cephalosporin antibiotic | ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) | 2006-08-29 | — | — | US | disclosed |
| EP-1618114-A2 | PROCESSES FOR THE PREPARATIONS OF CEFEPIME | Sandoz AG (CH) | 2006-01-25 | — | — | EP | disclosed |
| US-20050027118-A1 | Process for the preparation of a cephalosporin antibiotic | ORCHID CHEMICALS & PHARMACEUTICALS, LTD. (IN) | 2005-02-03 | — | — | US | disclosed |
| WO-2004111059-A1 | A PROCESS FOR THE PREPARATION OF A CEPHALOSPORIN ANTIBIOTIC | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2004-12-23 | — | — | WO | disclosed |
| WO-2004092183-A2 | PROCESSES FOR THE PREPARATIONS OF CEFEPIME | SANDOZ AG (CH) | 2004-10-28 | — | — | WO | disclosed |
| WO-2004083216-A1 | A PROCESS FOR THE PREPARATION OF CEPHALOSPORINS | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2004-09-30 | — | — | WO | disclosed |
| US-20040132995-A1 | Process for the preparation of cephalosporins | ORCHID CHEMICALS & PHARMACEUTICALS, LTD. (IN) | 2004-07-08 | — | — | US | disclosed |