Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5880313 | 1.00 | TSHR (0.32) | TSHR | |
| SCHEMBL3767455 | 1.00 | TSHR (0.32) | TSHR | |
| Hydrochloric Acid SCHEMBL5880365 | 0.98 | TSHR (0.31) | TSHR | |
| Trimethylammonium SCHEMBL27325918 | 0.94 | — | — | |
| SCHEMBL3767653 | 0.83 | — | — | |
| SCHEMBL14257118 | 0.83 | — | — | |
| SCHEMBL3767656 | 0.83 | — | — | |
| SCHEMBL6133165 | 0.81 | TSHR (0.31) | TSHR | |
| SCHEMBL3549809 | 0.81 | TSHR (0.31) | TSHR | |
| SCHEMBL3549805 | 0.81 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121494740-B | Method and device for cis-trans isomerism conversion of 4-halogen-2-methoxyimino acetoacetic acid ethyl ester | 山东金城医药化工有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-116393048-B | Continuous production system and production method of ethyl 4-chloro-2-methoxyiminoacetoacetate | 山东金城医药化工有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-116393048-A | Continuous production system and production method of ethyl 4-chloro-2-methoxyiminoacetoacetate | 山东金城医药化工有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-112010776-B | Method and device for continuously synthesizing 4-chloro-2-methoxyiminoacetoacetic acid ethyl ester | 上海应用技术大学 | 2023-04-28 | — | — | CN | claimed |
| CN-111978205-B | Method and device for continuously synthesizing 4-chloro-2-methoxyiminoacetoacetic acid ethyl ester | 上海应用技术大学 | 2023-04-28 | — | — | CN | claimed |
| CN-111100088-B | Method for continuously synthesizing ethyl dithiahydroxamate | 普洛药业股份有限公司 | 2022-06-21 | — | — | CN | claimed |
| CN-111100088-A | Method for continuously synthesizing ethyl dithiaoximate | 山东普洛得邦医药有限公司 | 2020-05-05 | — | — | CN | claimed |
| US-20020028931-A1 | Ceftiofur, its intermediate and a process for the preparation of the same | AUROBINDO PHARMA LIMITED (IN) | 2002-03-07 | — | — | US | claimed |
| EP-0842937-A2 | Process for the preparation of the cephalosporin derivatives cefotaxime and ceftriaxone | Hichem Pharma S.p.A. (IT) | 1998-05-20 | — | — | EP | claimed |
| US-4959495-A | Process for the preparation of intermediates used to produce aminothiazoloximino cephalosporins | AMERICAN CYANAMID COMPANY (US) | 1990-09-25 | — | — | US | claimed |
| EP-0257275-A2 | Cephalosporin and penicillin derivatives | AMERICAN CYANAMID COMPANY (US) | 1988-03-02 | — | — | EP | claimed |
| CN-121494740-B | Method and device for cis-trans isomerism conversion of 4-halogen-2-methoxyimino acetoacetic acid ethyl ester | 山东金城医药化工有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-116393048-B | Continuous production system and production method of ethyl 4-chloro-2-methoxyiminoacetoacetate | 山东金城医药化工有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116393048-A | Continuous production system and production method of ethyl 4-chloro-2-methoxyiminoacetoacetate | 山东金城医药化工有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-112010776-B | Method and device for continuously synthesizing 4-chloro-2-methoxyiminoacetoacetic acid ethyl ester | 上海应用技术大学 | 2023-04-28 | — | — | CN | disclosed |
| EP-0257275-A2 | Cephalosporin and penicillin derivatives | AMERICAN CYANAMID COMPANY (US) | 1988-03-02 | — | — | EP | disclosed |
| EP-0246603-A2 | 4-Halogeno-2-Oxyimino-3-Oxobutyric acids | Takeda Chemical Industries, Ltd. (JP) | 1987-11-25 | — | — | EP | disclosed |
| EP-0223246-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-05-27 | — | — | EP | disclosed |
| CN-86107947-A | New cephem compounds and preparation method thereof | — | 1987-05-27 | — | — | CN | disclosed |
| US-4166115-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028931-A1 | Ceftiofur, its intermediate and a process for the preparation of the same | BLVRB, CBR1, BTD | TSHR 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.