Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3767458 | 1.00 | TSHR (0.32) | TSHR | |
| SCHEMBL3767455 | 1.00 | TSHR (0.32) | TSHR | |
| Hydrochloric Acid SCHEMBL5880365 | 0.98 | TSHR (0.31) | TSHR | |
| Trimethylammonium SCHEMBL27325918 | 0.94 | — | — | |
| SCHEMBL3767653 | 0.83 | — | — | |
| SCHEMBL14257118 | 0.83 | — | — | |
| SCHEMBL3767656 | 0.83 | — | — | |
| SCHEMBL6133165 | 0.81 | TSHR (0.31) | TSHR | |
| SCHEMBL3549809 | 0.81 | TSHR (0.31) | TSHR | |
| SCHEMBL3549805 | 0.81 | TSHR (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959495-A | Process for the preparation of intermediates used to produce aminothiazoloximino cephalosporins | AMERICAN CYANAMID COMPANY (US) | 1990-09-25 | — | — | US | claimed |
| EP-0257275-A2 | Cephalosporin and penicillin derivatives | AMERICAN CYANAMID COMPANY (US) | 1988-03-02 | — | — | EP | claimed |
| US-7098329-B2 | Process for the preparation of a cephalosporin antibiotic | ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) | 2006-08-29 | — | — | US | disclosed |
| US-20050027118-A1 | Process for the preparation of a cephalosporin antibiotic | ORCHID CHEMICALS & PHARMACEUTICALS, LTD. (IN) | 2005-02-03 | — | — | US | disclosed |
| WO-2004111059-A1 | A PROCESS FOR THE PREPARATION OF A CEPHALOSPORIN ANTIBIOTIC | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2004-12-23 | — | — | WO | disclosed |
| WO-2004083216-A1 | A PROCESS FOR THE PREPARATION OF CEPHALOSPORINS | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2004-09-30 | — | — | WO | disclosed |
| US-20040132995-A1 | Process for the preparation of cephalosporins | ORCHID CHEMICALS & PHARMACEUTICALS, LTD. (IN) | 2004-07-08 | — | — | US | disclosed |
| US-5066799-A | Intermediates for the preparation of aminothiazoloximino cephalosporins | AMERICAN CYANAMID COMPANY (US) | 1991-11-19 | — | — | US | disclosed |
| US-4959495-A | Process for the preparation of intermediates used to produce aminothiazoloximino cephalosporins | AMERICAN CYANAMID COMPANY (US) | 1990-09-25 | — | — | US | disclosed |
| EP-0257275-A2 | Cephalosporin and penicillin derivatives | AMERICAN CYANAMID COMPANY (US) | 1988-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132995-A1 | Process for the preparation of cephalosporins | CYP2F1, CYP7A1, MRPL21 | TSHR 3849/4885 |
| US-20050027118-A1 | Process for the preparation of a cephalosporin antibiotic | SLC6A6, TST, TREH | TSHR 2627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.