SCHEMBL376794

SCHEMBL376794

Nc1ccc(C=Cc2ccc(NC(=O)c3ccccc3)cc2S(=O)(=O)O)c(S(=O)(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 2/20 0.53
▸ PRMT1 Q99873 3/20 0.52
▸ PLAU P00749 1/20 0.49
▸ RAD51 Q06609 1/20 0.48
▸ NPC1 O15118 5/20 0.48
▸ RAB9A P51151 5/20 0.48
▸ MAPT P10636 3/20 0.48
▸ MEN1 O00255 1/20 0.48
▸ TP53 P04637 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ CASP6 P55212 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ NSD2 O96028 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ POLB P06746 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ APEX1 P27695 1/20 0.47
▸ APOBEC3A P31941 1/20 0.47
▸ RECQL P46063 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL700458 1.00 ENPP2 (0.53) ENPP2PRMT1PLAURAD51NPC1
SCHEMBL29360736 1.00 ENPP2 (0.53) ENPP2PRMT1PLAURAD51NPC1
SCHEMBL29366447 0.92 ENPP2 (0.60) ENPP2PRMT1PLAURAD51NPC1
SCHEMBL5694392 0.92 ENPP2 (0.60) ENPP2PRMT1PLAURAD51NPC1
SCHEMBL5694390 0.92 ENPP2 (0.60) ENPP2PRMT1PLAURAD51NPC1
SCHEMBL9360369 0.92 PRMT1 (0.52) ENPP2PRMT1PLAUNPC1RAB9A
SCHEMBL9360377 0.92 PRMT1 (0.52) ENPP2PRMT1PLAUNPC1RAB9A
SCHEMBL7219219 0.92 PRMT1 (0.52) ENPP2PRMT1PLAURAD51NPC1
SCHEMBL11169136 0.90 ENPP2 (0.58) ENPP2PRMT1RAD51NPC1RAB9A
SCHEMBL29402666 0.89 POLB (0.58) ENPP2PRMT1RAD51NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9005988-B2 Method to assess multiphase fluid compositions LUX INNOVATE LIMITED (GB) 2015-04-14 — — US claimed
US-20110151576-A1 METHOD TO ASSESS MULTIPHASE FLUID COMPOSITIONS LUX INNOVATE LIMITED (GB) 2011-06-23 — — US claimed
US-20110104781-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2011-05-05 — — US claimed
US-20100233782-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2010-09-16 — — US claimed
WO-2010007390-A2 METHOD TO ASSESS MULTIPHASE FLUID COMPOSITIONS LUX INNOVATE LIMITED (GB) 2010-01-21 — — WO claimed
EP-2118129-A2 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES Life Technologies Corporation (US) 2009-11-18 — — EP claimed
US-20090161828-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES LIFE TECHNOLOGIES (US) 2009-06-25 — — US claimed
US-20080248565-A1 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES INVITROGEN CORPORATION (US) 2008-10-09 — — US claimed
WO-2008106660-A2 ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES INVITROGEN CORPORATION (US) 2008-09-04 — — WO claimed
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS INC (US) 2025-10-16 — — US disclosed
EP-4522646-A2 APOE LIPOPROTEIN SYSTEMS Kisbee Therapeutics, Inc. (US) 2025-03-19 — — EP disclosed
US-11921117-B2 Characterization of subvisible particles using a particle analyzer TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-03-05 — — US disclosed
WO-2023220387-A2 APOE LIPOPROTEIN SYSTEMS KISBEE THERAPEUTICS, INC. (US) 2023-11-16 — — WO disclosed
EP-3566649-B1 DEVICES FOR BLOOD SAMPLING YOURBIO HEALTH INC (US) 2023-06-07 — — EP disclosed
US-6030768-A Analysis of conformational changes in band 3 protein as a method for diagnosing Alzheimer's disease PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2000-02-29 — — US disclosed
US-5928841-A Method of photoetching at 180 to 220 KABUSHIKI KAISHA TOSHIBA (JP) 1999-07-27 — — US disclosed
WO-1999013725-A1 METHOD FOR DIAGNOSING ALZHEIMER'S DISEASE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1999-03-25 — — WO disclosed
US-5691101-A NONTOXIC PHOTORESISTS FOR MANUFACTURE OF CATHODE RAY TUBES AND IMAGE PICKUP DEVICES, ACID GENERATING COMPOUND WHICH CATALYZES CROSSLINKING OR DECOMPOSITION OF RESIN KABUSHIKI KAISHA TOSHIBA (JP) 1997-11-25 — — US disclosed
US-5007942-A Light-polarizing films or sheets containing stilbene dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1991-04-16 — — US disclosed
EP-0374655-A1 Light-polarising films or foils containing stilbene pigments BAYER AG (DE) 1990-06-27 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250319190-A1 APOE LIPOPROTEIN SYSTEMS APOB, APOL1, LDLR ENPP2 160/4885PRMT1 4858/4885PLAU 642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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