Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3853325 | 0.99 | NCF1 (0.40) | NCF1CHRM4KMT2ATDP1ALDH1A1 | |
| SCHEMBL3767256 | 0.85 | CHRM4 (0.43) | NCF1CHRM4ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL13874431 | 0.85 | CHRM4 (0.46) | NCF1CHRM4ALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3845747 | 0.85 | CHRM4 (0.42) | NCF1CHRM4ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3768008 | 0.85 | CHRM4 (0.38) | NCF1CHRM4KMT2AALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3849538 | 0.84 | CHRM4 (0.46) | NCF1CHRM4ALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3853437 | 0.84 | CHRM4 (0.38) | NCF1CHRM4KMT2AALDH1A1CYP1A2 | |
| SCHEMBL3851448 | 0.82 | NCF1 (0.45) | NCF1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL6637162 | 0.82 | NCF1 (0.45) | NCF1CHRM4ALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL5852112 | 0.81 | NCF1 (0.44) | NCF1KMT2AALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305065-A1 | USE OF 4-(PYRROLIDIN-1-YL)QUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS | HELPERBY THERAPEUTICS LIMITED (GB) | 2010-12-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305065-A1 | USE OF 4-(PYRROLIDIN-1-YL)QUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS | ARG1, LPO, CTSL | NCF1 892/4885CHRM4 1206/4885KMT2A 1981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.