Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SORD | Q00796 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765145 | 1.00 | RECQL (0.34) | RECQLSORDLMNAALDH1A1HPGD | |
| SCHEMBL875750 | 0.84 | KDM5A (0.33) | — | |
| SCHEMBL26942083 | 0.83 | CCNB2 (0.34) | LMNAMAPK1AXLPRKCI | |
| SCHEMBL23489752 | 0.80 | RECQL (0.33) | RECQLLMNAALDH1A1HPGDTSHR | |
| SCHEMBL27979580 | 0.79 | AXL (0.31) | AXLPRKCI | |
| SCHEMBL25322397 | 0.76 | ALDH1A1 (0.31) | RECQLLMNAALDH1A1HPGDTSHR | |
| SCHEMBL31145825 | 0.75 | KMO (0.30) | — | |
| SCHEMBL10677178 | 0.74 | AXL (0.32) | LMNAMAPK1AXLPRKCI | |
| SCHEMBL382323 | 0.73 | IDO1 (0.32) | — | |
| SCHEMBL4182232 | 0.73 | LMNA (0.44) | LMNAALDH1A1HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092009-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2025-03-20 | — | — | US | disclosed |
| US-20240254138-A1 | TRICYCLIC PYRIMIDINES AS CYCLIN-DEPENDENT KINASE 7 (CDK7) INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-08-01 | — | — | US | disclosed |
| CN-112424181-B | Substituted condensed thiophenes as STING modulators | 希泰克斯特私人有限公司 | 2024-02-27 | — | — | CN | disclosed |
| EP-4305040-A1 | TRICYCLIC PYRIDINES AS CYCLIN-DEPENDENT KINASE 7 (CDK7) INHIBITORS | JANSSEN Pharmaceutica NV (BE) | 2024-01-17 | — | — | EP | disclosed |
| EP-3793988-B1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-11-15 | — | — | EP | disclosed |
| CN-116940577-A | Tricyclic pyridines as cyclin dependent kinase 7 (CDK 7) inhibitors | 詹森药业有限公司 | 2023-10-24 | — | — | CN | disclosed |
| US-20230227423-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-07-20 | — | — | US | disclosed |
| US-20230227423-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-07-20 | — | — | US | disclosed |
| US-20230227423-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-07-20 | — | — | US | disclosed |
| US-11613525-B2 | Substituted condensed thiophenes as modulators of sting | CTXT PTY LIMITED (AU) | 2023-03-28 | — | — | US | disclosed |
| EP-3793988-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | Ctxt Pty Ltd (AU) | 2021-03-24 | — | — | EP | disclosed |
| CN-112424181-A | Substituted condensed thiophenes as STING modulators | 希泰克斯特私人有限公司 | 2021-02-26 | — | — | CN | disclosed |
| US-20170320870-A1 | COMPOUNDS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2017-11-09 | — | — | US | disclosed |
| US-20170320870-A1 | COMPOUNDS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2017-11-09 | — | — | US | disclosed |
| US-20170320870-A1 | COMPOUNDS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2017-11-09 | — | — | US | disclosed |
| WO-2017008708-A1 | METHOD FOR PREPARING INDAZOLE COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2017-01-19 | — | — | WO | disclosed |
| EP-2408772-B1 | COMPOUNDS | MEDICAL RES COUNCIL TECHNOLOGY (GB) | 2015-07-01 | — | — | EP | disclosed |
| US-20100317646-A1 | COMPOUNDS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-12-16 | — | — | US | disclosed |
| US-20100317646-A1 | COMPOUNDS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-12-16 | — | — | US | disclosed |
| US-20100317646-A1 | COMPOUNDS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227423-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | STING1, CGAS, IRF3 | RECQL 398/4885SORD 4870/4885LMNA 3433/4885 |
| US-20240254138-A1 | TRICYCLIC PYRIMIDINES AS CYCLIN-DEPENDENT KINASE 7 (CDK7) INHIBITORS | CDK7, CDK2, CCNK | RECQL 451/4885SORD 3054/4885LMNA 1633/4885 |
| US-20170320870-A1 | COMPOUNDS | CBR3, CNR1, HCAR3 | RECQL 2585/4885SORD 4592/4885LMNA 2925/4885 |
| US-11613525-B2 | Substituted condensed thiophenes as modulators of sting | STING1, CGAS, IRF3 | RECQL 472/4885SORD 4877/4885LMNA 3305/4885 |
| US-20100317646-A1 | COMPOUNDS | CBR3, CNR1, HCAR3 | RECQL 2593/4885SORD 4600/4885LMNA 2870/4885 |
| US-20250092009-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | STING1, CGAS, IRF3 | RECQL 398/4885SORD 4870/4885LMNA 3433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.