Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3760537 | 0.85 | KMT2A (0.54) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3762247 | 0.82 | CYP1A2 (0.64) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3772826 | 0.80 | CYP1A2 (0.61) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10277520 | 0.79 | CYP2C19 (0.44) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL3762594 | 0.76 | KMT2A (0.64) | KMT2ACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6865245 | 0.75 | CYP2C19 (0.41) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL3760544 | 0.75 | KMT2A (0.55) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18797641 | 0.73 | CYP1A2 (1.00) | KMT2AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6227253 | 0.73 | POLB (0.54) | CYP1A2CYP2C9CYP2C19KDM4EALDH1A1 | |
| SCHEMBL21936369 | 0.71 | POLB (0.53) | CYP1A2CYP2C9CYP2C19KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851570-B2 | Precatalysts useful in polyolefin polymerization reactions | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2010-12-14 | — | — | US | disclosed |
| US-20080207853-A1 | Precatalysts useful in polyolefin polymerization reactions | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207853-A1 | Precatalysts useful in polyolefin polymerization reactions | PPOX, PORCN, PTGES | KMT2A 2819/4885MEN1 3415/4885CYP1A2 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.