SCHEMBL3770571

SCHEMBL3770571

C[CH][SiH2]C(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4090948 0.79
SCHEMBL339299 0.76 THRB (0.36) THRBLMNA
SCHEMBL1066784 0.76 THRB (0.36) THRBLMNA
SCHEMBL4090915 0.75 DNM1 (0.33)
SCHEMBL15193882 0.72 THRB (0.33) THRBLMNA
SCHEMBL22191325 0.72 THRB (0.33) THRBLMNA
SCHEMBL4235363 0.72 THRB (0.33) THRBLMNA
SCHEMBL2931933 0.69 THRB (0.47) THRBLMNA
SCHEMBL25312206 0.69 THRB (0.31) THRB
SCHEMBL3891184 0.69 THRB (0.31) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6653365-B2 Polymerizable resin, a filler system comprising polyhedral polysilsesquioxane fillers, and a curing system; useful as crown and bridge materials, reconstructive or restorative materials PENTRON CLINICAL TECHNOLOGIES, LLC 2003-11-25 US claimed
US-20020198282-A1 Dental composite materials and method of manufacture thereof PENTRON CORPORATION 2002-12-26 US claimed
US-20240010901-A1 Thermally Conductive Polymer Composition TICONA LLC 2024-01-11 US disclosed
WO-2024010703-A1 THERMALLY CONDUCTIVE POLYMER COMPOSITION TICONA LLC (US) 2024-01-11 WO disclosed
WO-2023136990-A1 HIGH PERFORMANCE POLYMER COMPOSITION CONTAINING CARBON NANOSTRUCTURES TICONA LLC (US) 2023-07-20 WO disclosed
US-20230220182-A1 High Performance Polymer Composition Containing Carbon Nanostructures TICONA LLC 2023-07-13 US disclosed
US-10428262-B2 Nanoparticle modified fluids and methods of manufacture thereof BAKER HUGHES, A GE COMPANY, LLC (US) 2019-10-01 US disclosed
US-20180030332-A1 NANOPARTICLE MODIFIED FLUIDS AND METHODS OF MANUFACTURE THEREOF BAKER HUGHES, A GE COMPANY, LLC (US) 2018-02-01 US disclosed
US-9809740-B2 Nanoparticle modified fluids and methods of manufacture thereof BAKER HUGHES, A GE COMPANY, LLC (US) 2017-11-07 US disclosed
WO-2017078875-A1 NANOPARTICLE MODIFIED FLUIDS AND METHODS OF MANUFACTURE THEREOF BAKER HUGHES INCORPORATED (US) 2017-05-11 WO disclosed
US-20160060503-A1 NANOPARTICLE MODIFIED FLUIDS AND METHODS OF MANUFACTURE THEREOF BAKER HUGHES INCORPORATED (US) 2016-03-03 US disclosed
US-20060111465-A1 Dental glazes and method of manufacture and use thereof PENTRON CORPORATION 2006-05-25 US disclosed
US-20060009540-A1 Dental resins, dental composite materials, and method of manufacture thereof PENTRON CORPORATION 2006-01-12 US disclosed
US-20050173780-A1 Circuit materials, circuits, multi-layer circuits, and methods of manufacture thereof JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2005-08-11 US disclosed
WO-2005072031-A2 CIRCUIT MATERIALS, CIRCUITS, MULTI-LAYER CIRCUITS, AND METHODS OF MANUFACTURE THEREOF WORLD PROPERTIES, INC. (US) 2005-08-04 WO disclosed
US-20050038135-A1 Dental composite materials and method of manufacture thereof PENTRON CORPORATION 2005-02-17 US disclosed
US-20040262739-A1 Circuits, multi-layer circuits, and methods of manufacture thereof JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2004-12-30 US disclosed
WO-2004114732-A1 MATERIAL INCLUDING A LIQUID CRYSTALLINE POLYMER AND A POLYHEDRAL OLIGOMERIC SILSESQUIOXANE (POSS) FILLER WORLD PROPERTIES, INC. (US) 2004-12-29 WO disclosed
US-6653365-B2 Polymerizable resin, a filler system comprising polyhedral polysilsesquioxane fillers, and a curing system; useful as crown and bridge materials, reconstructive or restorative materials PENTRON CLINICAL TECHNOLOGIES, LLC 2003-11-25 US disclosed
US-20020198282-A1 Dental composite materials and method of manufacture thereof PENTRON CORPORATION 2002-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111465-A1 Dental glazes and method of manufacture and use thereof GLA, RARG, ECPAS THRB 3156/4885LMNA 45/4885
US-20060009540-A1 Dental resins, dental composite materials, and method of manufacture thereof MMAB, SMCHD1, CAD THRB 2550/4885LMNA 378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.