SCHEMBL4090915

SCHEMBL4090915

C[CH][SiH2]C(OCCCC)OCCCC

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
ATM Q13315 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4090948 0.86
SCHEMBL557068 0.80 TSHR (0.36) DNM1ADRB2ADRB1ADRB3ATM
SCHEMBL905272 0.80 DNM1 (0.32) DNM1ADRB2ADRB1ADRB3ATM
SCHEMBL3770571 0.75 THRB (0.38)
SCHEMBL7935124 0.74 DNM1 (0.39) DNM1ALDH1A1CNR1CNR2TSHR
SCHEMBL4092993 0.73 ADRB2 (0.38) DNM1ADRB2ADRB1ADRB3ATM
SCHEMBL7937310 0.72 DNM1 (0.42) DNM1ALDH1A1CNR1CNR2TSHR
SCHEMBL703587 0.71 ADRB2 (0.36) DNM1ADRB2ADRB1ADRB3ALDH1A1
SCHEMBL4092985 0.71 ADRB2 (0.36) DNM1ADRB2ADRB1ADRB3ALDH1A1
SCHEMBL703595 0.71 ADRB2 (0.36) DNM1ADRB2ADRB1ADRB3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090198028-A1 1,2-dithiol-3-thiones as chain-transfer agents in free-radical polymerization reactions BASF SE (DE) 2009-08-06 US disclosed
EP-2035464-A1 1,2-DITHIOL-3-THIONES AS CHAIN-TRANSFER AGENTS IN FREE-RADICAL POLYMERIZATION REACTIONS BASF SE (DE) 2009-03-18 EP disclosed
WO-2007147857-A1 1,2-DITHIOL-3-THIONES AS CHAIN-TRANSFER AGENTS IN FREE-RADICAL POLYMERIZATION REACTIONS BASF SE (DE) 2007-12-27 WO disclosed