Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3768594 | 0.89 | ALDH1A1 (0.41) | KEAP1SMN1; SMN2RAB9AHPGDDUSP3 | |
| SCHEMBL2503262 | 0.88 | CSNK2A2 (0.33) | KEAP1SMN1; SMN2RAB9AHRH3 | |
| SCHEMBL27840223 | 0.85 | HRH3 (0.38) | SMN1; SMN2RAB9AALDH1A1MAPK1CYP1A2 | |
| SCHEMBL3775966 | 0.85 | HRH3 (0.43) | SMN1; SMN2ALDH1A1MAPK1CYP1A2KCNH2 | |
| SCHEMBL2509146 | 0.83 | HRH3 (0.46) | SMN1; SMN2MAPK1CYP1A2KCNH2HRH3 | |
| SCHEMBL11647717 | 0.79 | KEAP1 (0.52) | KEAP1SMN1; SMN2RAB9AHPGDDUSP3 | |
| SCHEMBL13532385 | 0.78 | KEAP1 (0.56) | KEAP1SMN1; SMN2HPGDDUSP3ALDH1A1 | |
| SCHEMBL3773256 | 0.78 | USP2 (0.37) | KEAP1SMN1; SMN2RAB9AALDH1A1MAPK1 | |
| SCHEMBL20537222 | 0.76 | MAPT (0.31) | — | |
| SCHEMBL20536718 | 0.76 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436166-B2 | Amino-containing vinylsilane compounds and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20100317852-A1 | AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317852-A1 | AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD | BHMT2, GNMT, VASP | KEAP1 2182/4885SMN1; SMN2 3546/4885RAB9A 2703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.