SCHEMBL377258

SCHEMBL377258

O=C(O)Oc1ccncc1OC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
KDM4E B2RXH2 3/20 0.39
KDM4C Q9H3R0 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
KDM6B O15054 1/20 0.39
KDM4A O75164 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
KDM4D Q6B0I6 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NAPRT Q6XQN6 3/20 0.38
GAA P10253 2/20 0.38
HCAR2 Q8TDS4 2/20 0.38
APP P05067 1/20 0.38
HCAR3 P49019 1/20 0.38
CA12 O43570 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7603934 0.83 CA12 (0.39) ALDH1A1KDM4EKDM4CMEN1KMT2A
SCHEMBL4633602 0.82 ALDH1A1 (0.48) ALDH1A1KDM4EKDM4CMEN1KMT2A
SCHEMBL9413729 0.82 TDP1 (0.47) ALDH1A1KDM4EKDM4CMEN1KMT2A
SCHEMBL4633528 0.82 ALDH1A1 (0.53) ALDH1A1KDM4EKDM4CMEN1KMT2A
SCHEMBL9320822 0.82 GAA (0.41) ALDH1A1KDM4EKDM4CMEN1KMT2A
SCHEMBL485961 0.82 TDP1 (0.43) ALDH1A1KDM4EKDM4CMEN1KMT2A
SCHEMBL9572481 0.81 DYRK1A (0.43) ALDH1A1KDM4EKDM4CMEN1KMT2A
SCHEMBL9413735 0.79 CYP2E1 (0.38) ALDH1A1KDM4EKDM4CMEN1KMT2A
SCHEMBL8008655 0.77 SSTR4 (0.42) ALDH1A1KDM4ETDP1MAPTGAA
SCHEMBL9041579 0.75 KMT2A (0.50) ALDH1A1KDM4EKDM4CMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2949738-B1 LUBRICATING OIL COMPOSITION AND ADDITIVE THEREFOR HAVING IMPROVED WEAR PROPERTIES AFTON CHEMICAL CORP (US) 2021-01-13 EP claimed
EP-2739169-B1 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INST TECHNOLOGY (US) 2019-06-12 EP claimed
EP-3284847-B1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2019-01-02 EP claimed
EP-2557144-B1 Lubricant compositions containing a functionalized dispersant AFTON CHEMICAL CORP (US) 2018-06-06 EP claimed
EP-1529247-A1 USE OF SALTS OF LAYERED DOUBLE HYDROXIDES Clariant GmbH (DE) 2005-05-11 EP claimed
WO-2004019138-A1 USE OF SALTS OF LAYERED DOUBLE HYDROXIDES CLARIANT GMBH (DE) 2004-03-04 WO claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0150439-B1 AN ACID BATH FOR ELECTRODEPOSITION OF GOLD OR GOLD ALLOYS, AN ELECTROPLATING METHOD AND THE USE OF SAID BATH LeaRonal (UK) plc (GB) 1988-06-01 EP claimed
EP-1687462-B1 METHOD FOR ELECTROCHEMICAL PRODUCTION OF A CRYSTALLINE POROUS METAL ORGANIC SKELETON MATERIAL FRAUNHOFER GES FORSCHUNG (DE) 2019-03-13 EP disclosed
EP-2798013-B1 ANTI-REFLECTIVE COATING LEIBNIZ INST FÜR NEUE MATERIALIEN GEMEINNÜTZIGE GMBH (DE) 2016-08-17 EP disclosed
EP-2168971-B1 Fluid absorption by metal-organic frameworks BASF SE (DE) 2016-08-03 EP disclosed
EP-2230288-B1 METAL-ORGANIC FRAMEWORKS IN REFRIGERATION/HEATING MACHINES BASF SE (DE) 2016-05-25 EP disclosed
EP-2358922-B1 CONVERSION LAYERS FOR SURFACES CONTAINING ZINC ATOTECH DEUTSCHLAND GMBH (DE) 2016-01-27 EP disclosed
EP-0212705-A1 Record carrier for an electron beam Philips Patentverwaltung GmbH (DE) 1987-03-04 EP disclosed
EP-0192964-A2 Phthalocyanine reactive dyes BAYER AG (DE) 1986-09-03 EP disclosed
EP-0075905-B1 WATER-SOLUBLE REACTIVE PHTHALOCYANINE COMPOUNDS; PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-15 EP disclosed
EP-0145650-A1 1H-polyalkyl-phosphorinanes CIBA-GEIGY AG (CH) 1985-06-19 EP disclosed
EP-0140833-A1 5- and 6-Azaphthalides, their mixture of isomers, process for their production and their use in recording materials which are sensitive to pressure and heat CIBA-GEIGY AG (CH) 1985-05-08 EP disclosed
EP-0075905-A2 Water-soluble reactive phthalocyanine compounds; process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-04-06 EP disclosed