Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | AOC1 | P19801 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633528 | 0.89 | ALDH1A1 (0.53) | ALDH1A1KDM4ETDP1KDM4CMEN1 | |
| SCHEMBL377258 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KDM4ETDP1KDM4CMEN1 | |
| SCHEMBL4634558 | 0.80 | KDM4E (0.51) | ALDH1A1KDM4ETDP1KDM4CMEN1 | |
| SCHEMBL28281678 | 0.80 | KDM4E (0.44) | ALDH1A1KDM4ETDP1KDM4CMEN1 | |
| SCHEMBL8375858 | 0.79 | KDM4E (0.46) | ALDH1A1KDM4ETDP1KDM4CMEN1 | |
| SCHEMBL9413729 | 0.77 | TDP1 (0.47) | ALDH1A1KDM4ETDP1KDM4CMEN1 | |
| SCHEMBL8375135 | 0.75 | MEN1 (0.49) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL7603934 | 0.74 | CA12 (0.39) | ALDH1A1KDM4ETDP1KDM4CMEN1 | |
| Trifluoroacetic Acid SCHEMBL8375150 | 0.74 | KDM4E (0.39) | ALDH1A1KDM4ETDP1KDM4CMEN1 | |
| SCHEMBL9413735 | 0.74 | CYP2E1 (0.38) | ALDH1A1KDM4ETDP1KDM4CMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928868-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007028520-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-03-15 | — | — | WO | disclosed |
| EP-0059391-A1 | Imidazodiazepines, process for their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-09-08 | — | — | EP | disclosed |