Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485961 | 0.85 | TDP1 (0.43) | TDP1SIRT3POLBSSTR4PTGDR2 | |
| SCHEMBL10953461 | 0.85 | TDP1 (0.47) | TDP1SIRT3POLBSSTR4CHRNB2 | |
| SCHEMBL9413724 | 0.83 | SIRT3 (0.55) | TDP1SIRT3POLBSSTR4CHRNB2 | |
| SCHEMBL30600926 | 0.83 | SIRT3 (0.55) | TDP1SIRT3POLBSSTR4CHRNB2 | |
| SCHEMBL377258 | 0.82 | ALDH1A1 (0.39) | TDP1SIRT3KDM4CKDM4EALDH1A1 | |
| SCHEMBL27544390 | 0.81 | POLB (0.55) | POLBKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL29852333 | 0.80 | ACHE (0.50) | TDP1SIRT3SSTR4CHRNB2CHRNA4 | |
| SCHEMBL28080623 | 0.80 | SIRT3 (0.43) | TDP1SIRT3SSTR4KDM4CPTGS1 | |
| SCHEMBL9413735 | 0.78 | CYP2E1 (0.38) | TDP1PTGDR2KDM4CPTGS1PTGS2 | |
| SCHEMBL4633602 | 0.77 | ALDH1A1 (0.48) | TDP1SIRT3KDM4CKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602562-A1 | Process for the preparation of phthalocyanine reactive dyes | BASF Aktiengesellschaft (DE) | 1994-06-22 | — | — | EP | disclosed |
| EP-0527441-A2 | Water-soluble phthalocyanine dyes, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-02-17 | — | — | EP | disclosed |
| EP-0192964-B1 | PHTHALOCYANINE REACTIVE DYES | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0192964-A2 | Phthalocyanine reactive dyes | BAYER AG (DE) | 1986-09-03 | — | — | EP | disclosed |
| EP-0075905-B1 | WATER-SOLUBLE REACTIVE PHTHALOCYANINE COMPOUNDS; PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-15 | — | — | EP | disclosed |
| EP-0075905-A2 | Water-soluble reactive phthalocyanine compounds; process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-04-06 | — | — | EP | disclosed |