Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3773865 | 0.82 | PLA2G2A (0.41) | ALDH1A1LMNAPLA2G2AABCG2PRMT5 | |
| SCHEMBL3809767 | 0.79 | CYSLTR1 (0.41) | ALDH1A1LMNAPLA2G2AHTTMAPT | |
| SCHEMBL5810763 | 0.79 | MEN1 (0.46) | ALDH1A1LMNAPLA2G2AKDM4EHTT | |
| SCHEMBL3773863 | 0.78 | PLA2G2A (0.36) | ALDH1A1LMNAPLA2G2A | |
| SCHEMBL1401179 | 0.78 | PLA2G2A (0.36) | ALDH1A1LMNAPLA2G2A | |
| SCHEMBL1401053 | 0.78 | PLA2G2A (0.36) | ALDH1A1LMNAPLA2G2A | |
| SCHEMBL3779589 | 0.78 | PLA2G2A (0.36) | PLA2G2A | |
| SCHEMBL3780082 | 0.78 | ABCG2 (0.36) | ALDH1A1LMNAPLA2G2AABCG2 | |
| SCHEMBL4961177 | 0.75 | ALDH1A1 (0.46) | ALDH1A1LMNAKDM4ETP53MAPT | |
| SCHEMBL8604002 | 0.75 | CNR2 (0.38) | ALDH1A1LMNAKDM4ETP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006131782-A1 | PROCESS FOR THE MANUFACTURE OF METHYL-2-(3-(2-(7-CHLORO-2-QUINOLINYL-ETHENYL)-PHENYL)-3-OXOPROPYL) BENZOATE | GLADE ORGANICS PRIVATE LIMITED (IN) | 2006-12-14 | — | — | WO | disclosed |