Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281875 | 0.98 | BCHE (0.50) | BCHEACHE | |
| SCHEMBL7074344 | 0.96 | BCHE (0.54) | BCHEACHE | |
| SCHEMBL20066354 | 0.96 | BCHE (0.54) | BCHEACHE | |
| SCHEMBL9543168 | 0.85 | ALDH1A1 (0.42) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL11428687 | 0.83 | ALDH1A1 (0.44) | BCHEACHE | |
| Bromide SCHEMBL9463871 | 0.83 | ACHE (0.41) | BCHEACHE | |
| Iodide SCHEMBL3775515 | 0.83 | HTT (0.49) | — | |
| Hydrochloric Acid SCHEMBL28785382 | 0.81 | TSHR (0.53) | BCHEACHE | |
| SCHEMBL9586225 | 0.81 | NAAA (0.52) | BCHEACHE | |
| SCHEMBL5275740 | 0.81 | HTT (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855293-B2 | Fluorescent dyes such as 2-(4-acetanilino-1,3-butadieneyl)-3-spiro-1'-cyclohexan-1-(4-sulfobutyl)-3H -indolium hydroxide metal salts which couple biological materials without loss of fluorescence due to self-quenching | HAALCK LUTZ | 2010-12-21 | — | — | US | disclosed |
| US-20030138791-A1 | 3-Spiro-cyanin fluorochromes and their use in bioassays | HAALCK LUTZ (DE) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030138791-A1 | 3-Spiro-cyanin fluorochromes and their use in bioassays | SPR, CBR3, CIAPIN1 | ACHE 2414/4885BCHE 3408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.