SCHEMBL377461

SCHEMBL377461

O=C(O)Oc1cccnc1OC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.42
METAP2 P50579 1/20 0.42
METAP1 P53582 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HSP90AA1 P07900 1/20 0.40
KDM4E B2RXH2 4/20 0.39
TDP1 Q9NUW8 2/20 0.39
ALDH1A1 P00352 3/20 0.38
NPSR1 Q6W5P4 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
ALOX15 P16050 2/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
TSHR P16473 1/20 0.38
BLM P54132 1/20 0.38
AGER Q15109 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HTT P42858 1/20 0.38
CES2 O00748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8374606 0.87 ALDH1A1 (0.45) LMNAKDM4ETDP1ALDH1A1MAPT
SCHEMBL8338052 0.85 P2RY1 (0.39) LMNAMETAP2METAP1HDAC6HSP90AA1
Hydrochloric Acid SCHEMBL8374642 0.85 ALDH1A1 (0.44) LMNAKDM4ETDP1ALDH1A1MAPT
SCHEMBL4205798 0.84 TDP1 (0.55) KDM4ETDP1ALDH1A1MAPTKMT2A
SCHEMBL10802636 0.83 LMNA (0.36) LMNAMETAP2METAP1HDAC6HSP90AA1
SCHEMBL5702580 0.82 KDM4E (0.50) LMNAMETAP2METAP1HDAC6HSP90AA1
SCHEMBL8779417 0.81 LTA4H (0.55) L3MBTL1
SCHEMBL9226242 0.80 PTPN1 (0.44) LMNAHDAC6ALDH1A1L3MBTL1CYP3A4
SCHEMBL2304200 0.80 FTO (0.41) LMNAMETAP2METAP1KDM4ETDP1
SCHEMBL9030457 0.79 KDM4E (0.43) LMNAKDM4ETDP1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3701064-B1 A FORMULATION FOR CORROSION INHIBITION HINDUSTAN PETROLEUM CORP LTD (IN) 2023-07-19 EP claimed
EP-2949738-B1 LUBRICATING OIL COMPOSITION AND ADDITIVE THEREFOR HAVING IMPROVED WEAR PROPERTIES AFTON CHEMICAL CORP (US) 2021-01-13 EP claimed
EP-3236919-B1 PARTICULAR PYRIDINEDICARBOXYLIC ACID DERIVATIVE/ANTIOXIDANT COMBINATION OREAL (FR) 2019-10-16 EP claimed
EP-2823886-B1 Method of making hydroprocessing catalyst ADVANCED REFINING TECHNOLOGIES LLC (US) 2019-08-14 EP claimed
EP-2739169-B1 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INST TECHNOLOGY (US) 2019-06-12 EP claimed
EP-3284847-B1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2019-01-02 EP claimed
EP-3160228-B1 SYNERGISTIC ANTIMICROBIAL COMPOSITION OF ZINC PYRITHIONE JUBILANT LIFE SCIENCES LTD (IN) 2018-10-31 EP claimed
EP-2557144-B1 Lubricant compositions containing a functionalized dispersant AFTON CHEMICAL CORP (US) 2018-06-06 EP claimed
EP-1812523-B1 METAL ION-CONTAINING CMP COMPOSITION AND METHOD FOR USING THE SAME CABOT MICROELECTRONICS CORP (US) 2016-01-20 EP claimed
EP-1403339-B1 Black ink for inkjet recording FUJIFILM CORP (JP) 2013-03-06 EP claimed
EP-0462453-A2 Preparation of reactive dyes BAYER AG (DE) 1991-12-27 EP claimed
EP-0259687-B1 METHOD FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC ACIDS AMERICAN CYANAMID COMPANY (US) 1991-07-03 EP claimed
EP-0244167-B1 IMPROVED PROCESS FOR PREPARING POLY (ARYL ETHERS) AND POLY (ARYL ETHER KETONES) AMOCO CORPORATION (US) 1990-04-04 EP claimed
EP-0172140-B1 PROCESS FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES AND 1-AMINO-1,2,3,4-TETRAHYDRO-PYRIDINE-2,3-DICARBOXYLIC ACID DERIVATIVES AND 2,4-DIHYDROPYRIDINE-2,3-DICARBOXYLIC-ACID DERIVATIVES CIBA-GEIGY AG (CH) 1989-09-06 EP claimed
EP-0296109-A2 Derivatives of 2-(imidazolin-2-yl)nicotinic acid CIBA-GEIGY AG (CH) 1988-12-21 EP claimed
EP-0150439-B1 AN ACID BATH FOR ELECTRODEPOSITION OF GOLD OR GOLD ALLOYS, AN ELECTROPLATING METHOD AND THE USE OF SAID BATH LeaRonal (UK) plc (GB) 1988-06-01 EP claimed
EP-0145506-B1 ELIMINATION OF DEFECTS IN CYSTEINE-SENSITIZED EMULSIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-03-02 EP claimed
EP-0096444-B1 SELF-EXTINGUISHING POLYCARBONATE COMPOSITION ENICHEM TECNORESINE S.p.A. (IT) 1988-01-07 EP claimed
EP-0153908-A1 Process for the preparation of pyridine-2,3-dicarboxylic acid CIBA-GEIGY AG (CH) 1985-09-04 EP claimed
EP-0023371-B1 UNDERWATER COATING COMPOSITION ASTRAL Société de Peintures et Vernis (FR) 1983-08-31 EP claimed