Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.31 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481354 | 0.89 | GABBR2 (0.36) | BLMLMNACYP3A4NFKB1PMP22 | |
| SCHEMBL60413 | 0.84 | LMNA (0.39) | BLMLMNACYP3A4NFKB1PMP22 | |
| SCHEMBL17311823 | 0.81 | CYP1A2 (0.36) | BLMLMNACYP3A4NFKB1PMP22 | |
| SCHEMBL4059932 | 0.79 | SMPD1 (0.56) | FDPSSMPD1 | |
| SCHEMBL7840417 | 0.79 | SMPD1 (0.56) | FDPSSMPD1 | |
| SCHEMBL3775302 | 0.77 | FDPS (0.40) | BLMFDPSTDP1SMPD1 | |
| SCHEMBL17311820 | 0.76 | GSR (0.37) | BLMLMNACYP3A4NFKB1PMP22 | |
| SCHEMBL15102979 | 0.75 | GSR (0.36) | BLMLMNACYP3A4NFKB1PMP22 | |
| SCHEMBL15103003 | 0.75 | GSR (0.36) | BLMLMNACYP3A4NFKB1PMP22 | |
| SCHEMBL17311809 | 0.75 | GSR (0.36) | BLMLMNACYP3A4NFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1155387-C | Phosphonate medicine for treating osteoporosis and bone cancer transfer | 中国核动力研究设计院 | 2004-06-30 | — | — | CN | disclosed |
| CN-1302609-A | Phosphonate medicine for treating osteoporosis and bone cancer transfer | CHINESE DESIGN INST OF NUCLEAR (CN) | 2001-07-11 | — | — | CN | disclosed |