Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469727 | 0.80 | HPGD (0.43) | HPGDALDH1A1HSD17B10USP2MCL1 | |
| SCHEMBL11105965 | 0.80 | MCL1 (0.41) | HPGDALDH1A1HSD17B10USP2MCL1 | |
| SCHEMBL8986755 | 0.71 | HTR1A (0.36) | KMT2AMEN1HTR1ADRD2 | |
| SCHEMBL11207376 | 0.68 | HPGD (0.55) | HPGDALDH1A1HSD17B10USP2MCL1 | |
| SCHEMBL4850347 | 0.68 | HTR1A (0.55) | HPGDALDH1A1HSD17B10USP2CDK4 | |
| SCHEMBL4850625 | 0.66 | HSD17B10 (0.49) | HPGDALDH1A1HSD17B10USP2MCL1 | |
| SCHEMBL7345010 | 0.66 | HSD17B10 (0.46) | HPGDALDH1A1HSD17B10USP2MCL1 | |
| SCHEMBL12000241 | 0.65 | MCL1 (0.55) | HPGDALDH1A1HSD17B10USP2MCL1 | |
| SCHEMBL7005388 | 0.65 | HPGD (0.55) | HPGDALDH1A1HSD17B10USP2MCL1 | |
| SCHEMBL10675886 | 0.65 | ALDH1A1 (0.55) | HPGDALDH1A1HSD17B10USP2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408863-B1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | PROMEGA CORP (US) | 2018-01-10 | — | — | EP | disclosed |
| US-9458499-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458499-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458499-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |
| US-20160083782-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-03-24 | — | — | US | disclosed |
| US-20160083782-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-03-24 | — | — | US | disclosed |
| US-20160083782-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-03-24 | — | — | US | disclosed |
| US-9206474-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2015-12-08 | — | — | US | disclosed |
| US-9206474-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2015-12-08 | — | — | US | disclosed |
| US-9206474-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2015-12-08 | — | — | US | disclosed |
| US-8598198-B2 | Nucleic acid binding dyes and uses therefor | PROMEGA CORPORATION (US) | 2013-12-03 | — | — | US | disclosed |
| EP-2408863-A2 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | Promega Corporation (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010107816-A2 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | PROMEGA CORPORATION (US) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010107816-A2 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | PROMEGA CORPORATION (US) | 2010-09-23 | — | — | WO | disclosed |
| US-20100233710-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2010-09-16 | — | — | US | disclosed |
| US-20100233710-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2010-09-16 | — | — | US | disclosed |
| US-20100233710-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2010-09-16 | — | — | US | disclosed |
| EP-0040398-B1 | PROCESS FOR PREPARING 3-SUBSTITUTED 2(3H)-BENZOTHIAZOLONES OR 2(3H)-NAPHTHOTHIAZOLONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-01-16 | — | — | EP | disclosed |
| US-4429134-A | FROM CORRESPONDING IMINOBENZOTHIAZOLINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| EP-0040398-A2 | Process for preparing 3-substituted 2(3H)-benzothiazolones or 2(3H)-naphthothiazolones | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233710-A1 | NUCLEIC ACID BINDING DYES AND USES THEREFOR | POLRMT, POLB, POLL | HPGD 2883/4885ALDH1A1 898/4885HSD17B10 1753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.