Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NSD2 | O96028 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TDP2 | O95551 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65440 | 0.84 | ESR1 (0.58) | ALDH1A1HSD17B10TDP1CYP3A4TSHR | |
| SCHEMBL28581970 | 0.77 | CYP3A4 (0.81) | ALDH1A1HSD17B10TDP1CYP3A4HPGD | |
| Benzidine SCHEMBL29076656 | 0.74 | CYP3A4 (0.48) | ALDH1A1HSD17B10TDP1CYP3A4HPGD | |
| SCHEMBL48843 | 0.69 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TDP1CYP3A4HPGD | |
| SCHEMBL27912581 | 0.69 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TDP1CYP3A4HPGD | |
| SCHEMBL29365003 | 0.69 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TDP1CYP3A4HPGD | |
| SCHEMBL29286065 | 0.69 | LMNA (0.47) | ALDH1A1HSD17B10TDP1CYP3A4HPGD | |
| SCHEMBL3036362 | 0.68 | CYP3A4 (0.46) | ALDH1A1TDP1CYP3A4TSHRESR1 | |
| SCHEMBL9243328 | 0.68 | NR1H2 (0.45) | ALDH1A1TDP1CYP3A4TSHRESR1 | |
| SCHEMBL29052437 | 0.67 | ALDH1A1 (0.62) | ALDH1A1HSD17B10TDP1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858200-B2 | heat resistant layer containing a highly heat resistant polyimide and an adhesive layer on surface of heat-resistant layer which contains a thermoplastic polyimide; enables obtaining of a flexible metal clad laminate suppressed in dimensional change when produced by heat roll lamination; printed circuits | KANEKA CORPORATION (JP) | 2010-12-28 | — | — | US | disclosed |
| US-20080305346-A1 | heat resistant layer containing a highly heat resistant polyimide and an adhesive layer on surface of heat-resistant layer which contains a thermoplastic polyimide; enables obtaining of a flexible metal clad laminate suppressed in dimensional change when produced by heat roll lamination; printed circuits | KANEKA CORPORATION (JP) | 2008-12-11 | — | — | US | disclosed |