SCHEMBL3776555

SCHEMBL3776555

[O-][S+](c1ccc(Cl)cc1)N1CCC(F)CC1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
DPP4 P27487 2/20 0.32
DPP7 Q9UHL4 2/20 0.32
CCR5 P51681 1/20 0.32
POLB P06746 2/20 0.31
PSEN1 P49768 1/20 0.30
PSEN2 P49810 1/20 0.30
APH1B Q8WW43 1/20 0.30
NCSTN Q92542 1/20 0.30
APH1A Q96BI3 1/20 0.30
PSENEN Q9NZ42 1/20 0.30
DRD2 P14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3776684 0.90 DPP7 (0.34) LMNADPP4DPP7POLB
SCHEMBL3783418 0.90 DPP7 (0.34) LMNADPP4DPP7POLB
SCHEMBL3776598 0.84 MEN1 (0.30) POLB
SCHEMBL3774487 0.84 ATM (0.36) DPP4DPP7
SCHEMBL3776875 0.82 DPP7 (0.36) LMNADPP4DPP7POLBPSEN1
SCHEMBL3773093 0.82 DPP4 (0.34) DPP4DPP7
SCHEMBL3780104 0.82 CYP1A2 (0.32) LMNA
SCHEMBL3779703 0.81 RECQL (0.31)
SCHEMBL3785459 0.78 ACHE (0.35) LMNA
SCHEMBL3783104 0.77 POLB (0.41) LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100152463-A1 Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto IM&T RESEARCH, INC. (US) 2010-06-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152463-A1 Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto PFAS, AGPS, FDPS LMNA 2438/4885DPP4 2460/4885DPP7 1449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.