SCHEMBL3783418

SCHEMBL3783418

[O-][S+](c1ccc(Cl)cc1)N1CC[C@@H](F)C1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 3/20 0.34
DPP4 P27487 2/20 0.34
POLB P06746 1/20 0.32
LMNA P02545 1/20 0.31
FAAH O00519 1/20 0.31
GLA P06280 1/20 0.31
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3776684 1.00 DPP7 (0.34) DPP7DPP4POLBLMNAFAAH
SCHEMBL3776875 0.92 DPP7 (0.36) DPP7DPP4POLBLMNAGLA
SCHEMBL3776555 0.90 LMNA (0.33) DPP7DPP4POLBLMNA
SCHEMBL3776598 0.88 MEN1 (0.30) POLB
SCHEMBL3780172 0.85 DPP4 (0.35) DPP7DPP4NOTUM
SCHEMBL3783623 0.85 DPP4 (0.35) DPP7DPP4NOTUM
SCHEMBL3788604 0.83 DPP4 (0.38) DPP7DPP4
SCHEMBL3784221 0.83 CYP1A2 (0.33) DPP7DPP4
SCHEMBL3785187 0.83 CYP1A2 (0.33) DPP7DPP4
SCHEMBL1847673 0.83 DPP4 (0.32) DPP7DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100152463-A1 Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto IM&T RESEARCH, INC. (US) 2010-06-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152463-A1 Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto PFAS, AGPS, FDPS DPP7 1449/4885DPP4 2460/4885POLB 404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.