Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.48 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | SPR | P35270 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775088 | 0.92 | MAPT (0.50) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL3761098 | 0.88 | FAAH (0.58) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL3774633 | 0.87 | MAPT (0.52) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL12781817 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL12781801 | 0.86 | REV1 (0.52) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL18702024 | 0.86 | RAB9A (0.61) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL3765754 | 0.84 | RAB9A (0.66) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL18711777 | 0.84 | RAB9A (0.65) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL3774289 | 0.83 | MAPT (0.50) | SMN1; SMN2NPC1RAB9AFAAHLMNA | |
| SCHEMBL3760999 | 0.83 | RAB9A (0.66) | SMN1; SMN2NPC1RAB9AFAAHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851473-B2 | Amide compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-14 | — | — | US | disclosed |
| US-20080312226-A1 | Amide Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-18 | — | — | US | disclosed |
| CN-101103007-A | Amide compound | TAKEDA PHARMACEUTICAL (JP) | 2008-01-09 | — | — | CN | disclosed |
| EP-1813606-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312226-A1 | Amide Compound | FAAH, FAAH2, CNR2 | SMN1; SMN2 2454/4885NPC1 1078/4885RAB9A 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.