SCHEMBL377702

SCHEMBL377702

CC(C=O)(Cc1ccc(CS)cc1)N1CCOCC1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.37
ALDH1A1 P00352 5/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TSHR P16473 2/20 0.36
MAPK1 P28482 2/20 0.36
HIF1A Q16665 2/20 0.33
EPAS1 Q99814 2/20 0.33
GAA P10253 1/20 0.33
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
POLB P06746 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10526749 0.89 SIGMAR1 (0.37) SIGMAR1ALDH1A1SMN1; SMN2TSHRMAPK1
SCHEMBL28411123 0.87 AKR1C3 (0.43) SIGMAR1ALDH1A1SMN1; SMN2MAPK1NPC1
SCHEMBL5323322 0.86 KMT2A (0.40) SIGMAR1ALDH1A1SMN1; SMN2TSHRMAPK1
SCHEMBL12613218 0.85 ALDH1A1 (0.42) SIGMAR1ALDH1A1SMN1; SMN2TSHRMAPK1
SCHEMBL80420 0.84 SMN1; SMN2 (0.53) SIGMAR1ALDH1A1SMN1; SMN2TSHRMAPK1
SCHEMBL20723880 0.84 SMN1; SMN2 (0.53) SIGMAR1ALDH1A1SMN1; SMN2TSHRMAPK1
SCHEMBL28260274 0.83 MAPT (0.47) ALDH1A1SMN1; SMN2MAPK1GAANPC1
SCHEMBL29256744 0.81 SMN1; SMN2 (0.50) SIGMAR1ALDH1A1SMN1; SMN2TSHRMAPK1
SCHEMBL8518244 0.81 SMN1; SMN2 (0.41) SIGMAR1ALDH1A1SMN1; SMN2TSHRMAPK1
SCHEMBL14990403 0.80 ALDH1A1 (0.39) SIGMAR1ALDH1A1SMN1; SMN2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 705 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756420-B2 HIGH-SOLIDS COATING COMPOSITION WHICH COMPRISES (A) A COMPOUND WHICH HAS AT LEAST ONE RADICALLY POLYMERIZABLE UNSATURATED GROUP PER MOLECULE, (B) A HYDROXYL GROUP-CONTAINING ESTER COMPOUND WHICH IS OBTAINED BY ESTER-FORMING ADDITION REACTION KANSAI PAINT CO., LTD. (JP) 2004-06-29 US claimed
US-20030119980-A1 Coating composition and a process to form a coating film with use thereof KANSAI PAINT CO., LTD. (JP) 2003-06-26 US claimed
JP-4366111-A None JP disclosed
WO-2024142729-A1 RESIN COMPOSITION, LIQUID CRYSTAL SEALING AGENT, AND LIQUID CRYSTAL DISPLAY PANEL, AND PRODUCTION METHODS THEREOF 三井化学株式会社 2024-07-04 WO disclosed
US-12027666-B2 Electrolyte composition, electrolyte film, and method of manufacturing electrolyte film NIPPON SHOKUBAI CO., LTD. (JP) 2024-07-02 US disclosed
WO-2024134920-A1 INKJET INK COMPOSITION, RECORDED ARTICLE, INKJET RECORDING METHOD, AND INKJET RECORDING SYSTEM コニカミノルタ株式会社 2024-06-27 WO disclosed
WO-2024135615-A1 ELECTROLYTE COMPOSITION, ELECTROLYTE CURED ARTICLE OBTAINED BY CURING SAME, ELECTRODE, AND SECONDARY BATTERY 株式会社日本触媒 2024-06-27 WO disclosed
WO-2024135438-A1 ANAEROBIC CURING-TYPE ADHESIVE AGENT COMPOSITION, BONDED LAMINATE, AND MOTOR 東亞合成株式会社 2024-06-27 WO disclosed
EP-4389838-A1 ACTIVE-ENERGY-RAY-CURABLE COATING VARNISH, AND LAMINATE Artience Co., Ltd. (JP) 2024-06-26 EP disclosed
US-12019374-B2 Photosensitive resin structure for flexographic printing plate and method for producing flexographic printing plate ASAHI KASEI KABUSHIKI KAISHA (JP) 2024-06-25 US disclosed
WO-2024126332-A1 SACRIFICIAL ADDITIVELY MANUFACTURED MOLD WITH CONTROLLED MOISTURE AND LIQUID ABSORPTION PROPERTIES NEXA3D APS (DK) 2024-06-20 WO disclosed
US-5968681-A Polyether copolymer and polymer solid electrolyte DAISO CO., LTD (JP) 1999-10-19 US disclosed
EP-0897941-A1 CROSS-LINKED SOLID POLYELECTROLYTE AND USE THEREOF DAISO CO., LTD. (JP) 1999-02-24 EP disclosed
EP-0878482-A1 An active energy ray curable composition comprised of a maleimide derivative and a method for curing the said curable composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-11-18 EP disclosed
EP-0874012-A1 Coating composition for optical fiber TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-10-28 EP disclosed
EP-0856538-A1 SOLID POLYELECTROLYTE DAISO CO., LTD. (JP) 1998-08-05 EP disclosed
EP-0849296-A2 A photocurable resin composition and a method for producing the same TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-06-24 EP disclosed
EP-0838487-A2 Polyether copolymer and polymer solid electrolyte DAISO CO., LTD. (JP) 1998-04-29 EP disclosed
US-5612388-A Polyfunctional cationic monomer and process for producing the same NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1997-03-18 US disclosed
JP-H04366111-A COMPOSITION POLYMERIZABLE AND CURABLE BY VISIBLE RAY KANEBO LTD 1992-12-18 JP disclosed