SCHEMBL80420

SCHEMBL80420

CSc1ccc(CC(C)(C=O)N2CCOCC2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.53
ALDH1A1 P00352 2/20 0.53
TSHR P16473 2/20 0.53
MAPK1 P28482 2/20 0.53
PRKDC P78527 1/20 0.36
SLC6A4 P31645 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
RAB9A P51151 2/20 0.35
PAX8 Q06710 1/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
EPHX2 P34913 1/20 0.35
NR1H4 Q96RI1 1/20 0.35
KDM1A O60341 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20723880 1.00 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1TSHRMAPK1PRKDC
SCHEMBL29256744 0.96 SMN1; SMN2 (0.50) SMN1; SMN2ALDH1A1TSHRMAPK1PRKDC
Toluene SCHEMBL26110248 0.92 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1TSHRMAPK1RAB9A
SCHEMBL8518244 0.88 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1TSHRMAPK1SLC6A4
SCHEMBL28411123 0.86 AKR1C3 (0.43) SMN1; SMN2ALDH1A1MAPK1SLC6A4SIGMAR1
SCHEMBL10526749 0.84 SIGMAR1 (0.37) SMN1; SMN2ALDH1A1TSHRMAPK1SIGMAR1
SCHEMBL377702 0.84 SIGMAR1 (0.37) SMN1; SMN2ALDH1A1TSHRMAPK1SIGMAR1
SCHEMBL5323322 0.84 KMT2A (0.40) SMN1; SMN2ALDH1A1TSHRMAPK1SIGMAR1
SCHEMBL12613218 0.84 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1TSHRMAPK1SIGMAR1
SCHEMBL28818856 0.83 SMN1; SMN2 (0.50) SMN1; SMN2ALDH1A1TSHRMAPK1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2019 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4502064-A1 CURABLE COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2025-02-05 EP claimed
US-20250034429-A1 CURABLE COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2025-01-30 US claimed
WO-2024225464-A1 CURABLE COMPOSITION ダイキン工業株式会社 2024-10-31 WO claimed
WO-2024225461-A1 CURABLE COMPOSITION ダイキン工業株式会社 2024-10-31 WO claimed
WO-2024042535-A1 HEMOSTATIC COMPOSITE, ITS METHOD AND APPLICATIONS THEREOF JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2024-02-29 WO claimed
CN-115181268-B Photosensitive polyimide, preparation method thereof and photosensitive polyimide composition 深圳市深职材料技术有限公司 2023-11-10 CN claimed
WO-2023190766-A1 CURABLE COMPOSITION ダイキン工業株式会社 2023-10-05 WO claimed
WO-2023190725-A1 CURABLE COMPOSITION ダイキン工業株式会社 2023-10-05 WO claimed
WO-2023190723-A1 CURABLE COMPOSITION ダイキン工業株式会社 2023-10-05 WO claimed
WO-2023190742-A1 CURABLE COMPOSITION ダイキン工業株式会社 2023-10-05 WO claimed
US-6022907-A POLYESTERURETHANE FROM DIMER ACIDS, REACTIVE END GROUPSA KYOEISHA CHEMICAL CO., LTD. (JP) 2000-02-08 US claimed
EP-0963420-A1 RADIATION-CURABLE, CYANOACRYLATE-CONTAINING COMPOSITIONS LOCTITE CORPORATION (US) 1999-12-15 EP claimed
WO-1998038260-A9 RADIATION-CURABLE, CYANOACRYLATE-CONTAINING COMPOSITIONS 1999-02-11 WO claimed
EP-0882749-A2 Urethane prepolymer, process for producing the same and pressure-sensitive adhesive comprising the same KYOEISHA CHEMICAL CO., LTD. (JP) 1998-12-09 EP claimed
WO-1998038260-A1 RADIATION-CURABLE, CYANOACRYLATE-CONTAINING COMPOSITIONS LOCTITE CORPORATION (US) 1998-09-03 WO claimed
EP-0646552-B1 Method of curing dual-coated optical fiber AT & T CORP (US) 1997-12-17 EP claimed
US-5371116-A Long self life SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-12-06 US claimed
US-5100767-A Epoxy resins TAMURA KAKEN CO., LTD. (JP) 1992-03-31 US claimed
US-4994703-A Piezoelectric element of laminate type MITSUBISHI KASEI CORPORATION (JP) 1991-02-19 US claimed
US-4910232-A Ultraviolet-curable organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-03-20 US claimed