Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28411123 | 0.87 | AKR1C3 (0.43) | KMT2ASMN1; SMN2MEN1NPC1ALDH1A1 | |
| SCHEMBL377702 | 0.86 | SIGMAR1 (0.37) | SMN1; SMN2NPC1ALDH1A1RAB9ASIGMAR1 | |
| SCHEMBL10526749 | 0.86 | SIGMAR1 (0.37) | SMN1; SMN2NPC1ALDH1A1RAB9ASIGMAR1 | |
| SCHEMBL12613218 | 0.85 | ALDH1A1 (0.42) | KMT2ASMN1; SMN2MEN1ALDH1A1SIGMAR1 | |
| SCHEMBL80420 | 0.84 | SMN1; SMN2 (0.53) | KMT2ASMN1; SMN2MEN1ALDH1A1RAB9A | |
| SCHEMBL20723880 | 0.84 | SMN1; SMN2 (0.53) | KMT2ASMN1; SMN2MEN1ALDH1A1RAB9A | |
| SCHEMBL28260274 | 0.83 | MAPT (0.47) | KMT2ASMN1; SMN2MEN1NPC1ALDH1A1 | |
| SCHEMBL29256744 | 0.81 | SMN1; SMN2 (0.50) | KMT2ASMN1; SMN2MEN1ALDH1A1RAB9A | |
| SCHEMBL8518244 | 0.81 | SMN1; SMN2 (0.41) | KMT2ASMN1; SMN2MEN1ALDH1A1RAB9A | |
| SCHEMBL8735163 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2NPC1ALDH1A1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113833-A2 | MINIMALLY INVASIVE SYSTEM FOR TREATING HOLLOW ORGAN DILATATION | CAHAN AMOS (IL) | 2007-10-11 | — | — | WO | disclosed |