Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957496 | 1.00 | MEN1 (0.47) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL11058152 | 0.94 | MEN1 (0.50) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL11058834 | 0.94 | MEN1 (0.50) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL11057233 | 0.94 | MEN1 (0.50) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9542975 | 0.94 | ALDH1A1 (0.50) | ALDH1A1CA1CA2CA9CA12 | |
| SCHEMBL11228544 | 0.94 | ALDH1A1 (0.50) | ALDH1A1CA1CA2CA9CA12 | |
| SCHEMBL11232260 | 0.94 | ALDH1A1 (0.50) | ALDH1A1CA1CA2CA9CA12 | |
| SCHEMBL1774885 | 0.94 | ALDH1A1 (0.50) | ALDH1A1CA1CA2CA9CA12 | |
| SCHEMBL36624 | 0.94 | ALDH1A1 (0.50) | ALDH1A1CA1CA2CA9CA12 | |
| SCHEMBL273330 | 0.94 | ALDH1A1 (0.50) | ALDH1A1CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100312003-A1 | METHOD FOR THE PREPARATION OF ORGANIC NITRATES | LONZA LTD. (CH) | 2010-12-09 | — | — | US | disclosed |
| EP-2200966-A1 | METHOD FOR THE PREPARATION OF ORGANIC NITRATES | LONZA LTD. (CH) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009046992-A1 | METHOD FOR THE PREPARATION OF ORGANIC NITRATES | LONZA LTD (CH) | 2009-04-16 | — | — | WO | disclosed |
| EP-2048129-A1 | Method for the preparation of organic nitrates | LONZA AG (CH) | 2009-04-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100312003-A1 | METHOD FOR THE PREPARATION OF ORGANIC NITRATES | NOS2, NOS1, NOS3 | MEN1 3329/4885THRB 3083/4885HTT 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.