Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.78 |
| ▸ | PTGES | O14684 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | PLEC | Q15149 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27947220 | 0.89 | KDR (1.00) | KDRMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL29510019 | 0.89 | KDR (1.00) | KDRMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL3777404 | 0.83 | PTGES (1.00) | PTGESMEN1KMT2AMAPTTP53 | |
| SCHEMBL3764456 | 0.81 | PTGES (0.78) | KDRPTGESMEN1KMT2AL3MBTL1 | |
| SCHEMBL3770882 | 0.81 | KCNK3 (0.66) | PTGESMEN1KMT2AMAPTKCNK3 | |
| SCHEMBL30753823 | 0.80 | L3MBTL1 (1.00) | KDRMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL28267081 | 0.80 | L3MBTL1 (1.00) | KDRMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL27803940 | 0.79 | KDR (0.81) | KDRMEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL13010684 | 0.78 | PTGES (0.82) | PTGESMEN1KMT2AMAPTTP53 | |
| SCHEMBL6260903 | 0.78 | KDR (1.00) | KDRMEN1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | claimed |
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | IL1B, LITAF, CYP11B1 | KDR 4001/4885PTGES 54/4885MEN1 668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.