SCHEMBL3778063

SCHEMBL3778063

CC(C)(C)[SiH2]OC(C)(C)C1CN(Cc2ccccc2)CCC1O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
SLC18A3 Q16572 6/20 0.44
FUCA1 P04066 2/20 0.43
ACHE P22303 1/20 0.43
SIGMAR1 Q99720 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6042627 0.87 ALDH1A1 (0.43) ALDH1A1SLC18A3FUCA1ACHE
SCHEMBL30994643 0.80 ALDH1A1 (0.54) ALDH1A1SLC18A3FUCA1ACHE
SCHEMBL1869073 0.80 ACHE (0.39) ALDH1A1ACHE
SCHEMBL7226356 0.76 ALDH1A1 (0.55) ALDH1A1SLC18A3FUCA1ACHESIGMAR1
SCHEMBL5157969 0.74 FUCA1 (0.66) ALDH1A1SLC18A3FUCA1ACHESIGMAR1
SCHEMBL5157349 0.74 FUCA1 (0.66) ALDH1A1SLC18A3FUCA1ACHESIGMAR1
SCHEMBL7226969 0.73 ACHE (0.60) ALDH1A1SLC18A3FUCA1ACHESIGMAR1
SCHEMBL10267804 0.73 ACHE (0.60) ALDH1A1SLC18A3FUCA1ACHESIGMAR1
SCHEMBL765298 0.73 ACHE (0.60) ALDH1A1SLC18A3FUCA1ACHESIGMAR1
SCHEMBL914717 0.73 ACHE (0.60) ALDH1A1SLC18A3FUCA1ACHESIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100324030-A1 5-Quinoline derivatives having an anti-bacterial activity MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) 2010-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100324030-A1 5-Quinoline derivatives having an anti-bacterial activity TOP2A, TOP1, TOP2B ALDH1A1 3016/4885SLC18A3 4224/4885FUCA1 2749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.