Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | BACE1 | P56817 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30994643 | 0.84 | ALDH1A1 (0.54) | ALDH1A1FUCA1SLC18A3ACHEBCHE | |
| SCHEMBL5157349 | 0.82 | FUCA1 (0.66) | ALDH1A1FUCA1SLC18A3ACHEBCHE | |
| SCHEMBL5157969 | 0.82 | FUCA1 (0.66) | ALDH1A1FUCA1SLC18A3ACHEBCHE | |
| SCHEMBL27890303 | 0.82 | ACHE (0.49) | ALDH1A1ACHEBCHEBACE1SIGMAR1 | |
| SCHEMBL1963928 | 0.81 | ALDH1A1 (0.58) | ALDH1A1FUCA1SLC18A3ACHEBCHE | |
| SCHEMBL30195485 | 0.81 | ALDH1A1 (0.58) | ALDH1A1FUCA1SLC18A3ACHEBCHE | |
| SCHEMBL28304829 | 0.80 | ACHE (0.53) | ALDH1A1ACHEBCHEBACE1SIGMAR1 | |
| SCHEMBL28304830 | 0.80 | ACHE (0.53) | ALDH1A1ACHEBCHEBACE1SIGMAR1 | |
| Methylene Chloride SCHEMBL27890328 | 0.79 | ACHE (0.47) | ALDH1A1ACHEBCHEBACE1SIGMAR1 | |
| SCHEMBL3846308 | 0.78 | ALDH1A1 (0.58) | ALDH1A1FUCA1SLC18A3ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102702080-B | Preparation method of 3-trifluoromethyl piperidine derivatives | YANGZHOU FUYAO TECHNOLOGY CO LTD | 2014-02-19 | — | — | CN | disclosed |
| CN-102702080-A | Preparation method of 3-trifluoromethyl piperidine derivatives | YANGZHOU FUYAO TECHNOLOGY CO LTD | 2012-10-03 | — | — | CN | disclosed |
| US-6608078-B2 | Gramnegative bacteria | WOCKHARDT LIMITED (IN) | 2003-08-19 | — | — | US | disclosed |
| US-20020165227-A1 | Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment | WOCKHARDT RESEARCH CENTER | 2002-11-07 | — | — | US | disclosed |
| WO-2001085728-A2 | ANTIBACTERIAL CHIRAL 8-(SUBSTITUTED PIPERIDINO)-BENZO [I, J] QUINOLIZINES, PROCESSES, COMPOSITIONS AND METHODS OF TREATMENT | WOCKHARDT LIMITED (IN) | 2001-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165227-A1 | Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment | ALPI, POLR1C, POLI | ALDH1A1 2656/4885FUCA1 1778/4885SLC18A3 4469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.