SCHEMBL377888

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL378086	0.92	BRD4 (0.77)	BRD4IL17AACHEPARP1BRD1
	SCHEMBL378031	0.92	BRD4 (0.77)	BRD4IL17AACHEPARP1BRD1
	SCHEMBL377819	0.89	BRD4 (0.53)	BRD4IL17APARP1BRD1BRD2
	SCHEMBL378520	0.85	BRD4 (0.59)	BRD4IL17AACHEMMP13CHEK2
	SCHEMBL377845	0.84	BRD4 (0.61)	BRD4IL17APARP1BRD1BRD2
	SCHEMBL377913	0.84	BRD4 (0.61)	BRD4IL17APARP1BRD1BRD2
	SCHEMBL378077	0.83	BRD4 (0.81)	BRD4IL17AACHEPARP1BRD1
	SCHEMBL30054250	0.83	BRD4 (0.81)	BRD4IL17AACHEPARP1BRD1
	SCHEMBL347132	0.79	BRD4 (1.00)	BRD4IL17APARP1HDAC1HDAC3
	SCHEMBL30052302	0.79	BRD4 (1.00)	BRD4IL17APARP1HDAC1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.